BCL2L1 anticorps (PE)
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- Antigène Voir toutes BCL2L1 Anticorps
- BCL2L1 (BCL2-Like 1 (BCL2L1))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp BCL2L1 est conjugé à/à la PE
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Application
- Flow Cytometry (FACS)
- Specificité
- Human/Mouse/Rat/Rhesus Bcl-xL
- Attributs du produit
- Mouse Anti-Bcl-xL-PE
- Immunogène
- Recombinant human Bcl-xS
- Clone
- 7B2-5
- Isotype
- IgG3
- Top Product
- Discover our top product BCL2L1 Anticorps primaire
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- Indications d'application
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- Applications: FC - Quality tested , IHC-PS - Reported in literature , ICC - Reported in literature , WB - Reported in literature , IP - Reported in literature , ELISA - Reported in literature
- Working Dilutions: Flow Cytometry FITC and BIOT conjugates 3 g/106 cells PE conjugate 0.3 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L Immunoblotting Purified (UNLB) antibody 1 g/mL
- Volume d'échantillon
- 1 mL
- Restrictions
- For Research Use only
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- Concentration
- 0.1 mg/mL
- Buffer
- 0.1 mg in 1.0 mL of PBS/Sodium azide and a stabilizing agent
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
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Do not freeze!
Protect conjugated products from light.
Each reagent is stable for the period shown on the bottle label if stored as directed. - Stock
- 4 °C
- Stockage commentaire
- Store at 2-8°C
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A universal strategy for adoptive immunotherapy of cancer through use of a novel T cell antigen receptor." dans: Cancer research, (2012) (PubMed).
: "The ability of Bcl-x(L) and Bcl-2 to prevent apoptosis can be differentially regulated." dans: Cell death and differentiation, Vol. 3, Issue 1, pp. 113-8, (2006) (PubMed).
: "
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A universal strategy for adoptive immunotherapy of cancer through use of a novel T cell antigen receptor." dans: Cancer research, (2012) (PubMed).
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- Antigène
- BCL2L1 (BCL2-Like 1 (BCL2L1))
- Autre désignation
- Bcl-xL (BCL2L1 Produits)
- Synonymes
- anticorps BCL-XL/S, anticorps BCL2L, anticorps BCLX, anticorps BCLXL, anticorps BCLXS, anticorps Bcl-X, anticorps PPP1R52, anticorps bcl-xL, anticorps bcl-xS, anticorps Bcl(X)L, anticorps Bcl-XL, anticorps Bcl-Xs, anticorps Bcl2l, anticorps BclX, anticorps bcl-x, anticorps Bcl-xl, anticorps Bclx, anticorps bcl-X, anticorps Bcl-xL, anticorps BCL-XL, anticorps BCL2L1, anticorps bcl-XL, anticorps bcl-x(l), anticorps bcl-xl/s, anticorps bcl-xs, anticorps bcl2l, anticorps bclx, anticorps bclxl, anticorps xR11, anticorps bcl-xl, anticorps blp1, anticorps cb1021, anticorps zfBLP1, anticorps BCL2 like 1, anticorps BCL2-like 1, anticorps Bcl2-like 1, anticorps BCL2-like 1 L homeolog, anticorps bcl2-like 1, anticorps BCL2L1, anticorps Bcl2l1, anticorps bcl2l1, anticorps bcl2l1.L
- Sujet
- Apoptosis, or programmed cell death, is a well-documented phenomenon in many cellular systems. It plays a key role in tissue and organ development as well as in adult tissues during cell turnover. Apoptosis can be induced by a variety of internal and external stimuli including growth factor deprivation, cytokine treatment, antigen-receptor engagement, cell-cell interactions, irradiation and glucocorticoid treatment. Bcl-2 and one of its homologues, Bcl-xL, protect cells from apoptosis, while other homologues of Bcl-2 such as Bax, Bad and Bak have been shown to enhance apoptosis. Bcl-xL has been shown to block apoptosis which is induced by a variety of stimuli and, under certain conditions, offers greater protection against apoptosis than Bcl-2. In contrast, Bad and Bax inhibit the protective functions of Bcl-xL and Bcl-2, respectively. Although heterodimerization between Bcl-xL/Bad and Bcl-2/Bax was originally thought to be essential for the differential anti-apoptotic activity of Bcl-xL and Bcl-2, other results suggest that the formation of heterodimers may not be necessary for this death-repressing activity.
- Pathways
- Apoptose, Negative Regulation of intrinsic apoptotic Signaling
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