Fibrillin anticorps

N° du produit ABIN135062

Détail du produit anti-Fibrillin anticorps

Antigène: Fibrillin (FBL)

Reactivité: Boeuf (Vache), Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Fibrillin est non-conjugé

Application: Immunohistochemistry (IHC), Western Blotting (WB), Immunocytochemistry (ICC)

Attributs du produit: The antibody detects: Human and bovine fibrillin (Mr 350 kDa), other species not tested
In immunohistochemical staining of paraformaldehyde-fixed human skin, mAb 11C1.3 labels the elastic framework and more specifically the oxytalantic network close to the epidermis. The antibody also exhibits discrete staining of normal fibroblasts in culture and of extracellular (elastin) fibrils in a variety of tissues. There is an aberrant expression of fibrillin in Marfan syndrome.

Purification: Purified

Immunogène: Microfibrils from zonular apparatus of bovine eye Ig

Clone: 11C1-3

Isotype: IgG1

Information d'application

Indications d'application: Working Dilution:
Immunohistochemistry: 1:50-1:100 (30-60 min at RT)
Representative data are included in this product insert.

Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.

Volume d'échantillon: 1 mL

Restrictions: For Research Use only

Stockage

Buffer: Product is supplied as 0.2 mg of purified immunoglobulin in 1.0 mL of 100 mM borate buffered saline, pH 8.0.

Agent conservateur: Azide free

Conseil sur la manipulation: Each reagent is stable for the period shown on the bottle label if stored as directed.

Stock: 4 °C

Détails sur Fibrillin

Antigène: Fibrillin (FBL)

Autre désignation: Fibrillin (FBL Produits)

Synonymes: anticorps T24H24.16, anticorps T24H24_16, anticorps fibrillin, anticorps fibrillin, anticorps hypothetical protein, anticorps fibrillar structure forming protein, anticorps FIB, anticorps T26E3.6, anticorps ORF-18 p10

Sujet: The fibrillins are extracellular matrix glycoproteins which occur as a major component of a subset of connective tissue microfibrils. These microfibrils have a beaded appearance and a cross-sectional diameter of 10-12 nm. In elastic tissues, these structures are thought to provide the scaffold onto which elastin is assembled to form elastic fibers, although their function in non-elastic tissues is unclear.