CD28 anticorps
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- Antigène Voir toutes CD28 Anticorps
- CD28
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Reactivité
- Souris
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Hôte
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Hamster
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD28 est non-conjugé
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Application
- Flow Cytometry (FACS)
- Specificité
- Mouse CD28, Mr 40 kDa
- Attributs du produit
- Hamster Anti-Mouse CD28-LE/AF
- niveau d'endotoxine
- Low endotoxin
- Immunogène
- C57BL/6N mouse T cell lymphoma EL4 cell line
- Clone
- PV-1
- Isotype
- IgG
- Top Product
- Discover our top product CD28 Anticorps primaire
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- Indications d'application
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- Applications: FC - Quality tested , IP - Reported in literature , Costim - Reported in literature , Stim - Reported in literature
- Working Dilutions: Flow Cytometry FITC and BIOT conjugates 3 g/106 cells PE, APC, and SPRD conjugates 0.3 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
- Commentaires
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In vitro costimulation of T cells and NK cells
- Volume d'échantillon
- 1 mL
- Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- 0.5 mg of purified immunoglobulin in 1.0 mL of PBS
- Agent conservateur
- Azide free
- Conseil sur la manipulation
- Each reagent is stable for the period shown on the bottle label if stored as directed.
- Stock
- -20 °C
- Stockage commentaire
- Aliquot and freeze the low endotoxin, azide-free product at -20 °C immediately upon receipt.
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- Antigène
- CD28
- Autre désignation
- CD28 (CD28 Produits)
- Sujet
- CD28 is a type I disulfide-linked homodimer that is constitutively expressed on most thymocytes, at low density on nearly all CD4+ and CD8+ peripheral T lymphocytes, and at very low levels on NK cells. Its expression is upregulated upon T-cell activation. CD28 is a ligand for CD80/B7-1 and CD86/B7-2 on B cells and other antigen presenting cells, and plays an important role in the interaction between T cells and B cells. CD28 is a co-stimulatory receptor involved in many, but not all, T-cell independent immune responses.
- Pathways
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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