CD69 anticorps (FITC)

N° du produit ABIN135255

Détail du produit anti-CD69 anticorps (FITC)

Antigène: CD69

Reactivité: Souris

Hôte: Hamster

Clonalité: Monoclonal

Conjugué: Cet anticorp CD69 est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Specificité: Mouse CD69, Mr 85 kDa (unreduced)

Attributs du produit: Hamster Anti-Mouse CD69-FITC

Purification: Protein A

Immunogène: Mouse dendritic epidermal cell line Y245

Clone: H1-2F3

Isotype: IgG

Information d'application

Indications d'application:

• Applications: FC - Quality tested , IHC-FS - Reported in literature , IP - Reported in literature , Costim - Reported in literature , Activ - Reported in literature
• Working Dilutions: Flow Cytometry FITC, BIOT, and AF488 conjugates 1 g/106 cells PE, APC, SPRD, PE/CY7, AF647, and PACBLU conjugates 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

Commentaires:

In vitro T cell and NK-cell activation

Volume d'échantillon: 1 mL

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: 0.5 mg in 1.0 mL of PBS/Sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect conjugated products from light.
Each reagent is stable for the period shown on the bottle label if stored as directed.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C

Références pour anticorps anti-CD69 (FITC) (ABIN135255)

Waaler, Mygland, Tveita, Strand, Solberg, Olsen, Aizenshtadt, Fauskanger, Lund, Brinch, Lycke, Dybing, Nygaard, Bøe, Heintz, Hovig, Hammarström, Corthay, Krauss: "Tankyrase inhibition sensitizes melanoma to PD-1 immune checkpoint blockade in syngeneic mouse models." dans: Communications biology, Vol. 3, Issue 1, pp. 196, (2020) (PubMed).

Détails sur CD69

Antigène: CD69

Autre désignation: CD69 (CD69 Produits)

Synonymes: anticorps 5830438K24Rik, anticorps AI452015, anticorps AIM, anticorps VEA, anticorps BL-AC/P26, anticorps CLEC2C, anticorps EA1, anticorps GP32/28, anticorps MLR-3, anticorps Cd69 molecule, anticorps CD69 antigen, anticorps CD69 molecule, anticorps Cd69, anticorps CD69

Sujet: CD69, also known as very early activation (VEA) antigen, is a disulfide-linked transmembrane homodimer whose differentially glycosylated subunits range from 35-39 kDa. It is a C-type lectin, most closely related to the NKR-P1 and Ly-49 NK cell-activation molecules. CD69 is widely expressed on hematopoietic cells, including lymphocytes, neutrophils and eosinophils. Although not detectable on resting lymphocytes, its expression is rapidly (within 2 hours) upregulated upon activation of T, B and NK cells, and neutrophils.4 Constitutive expression of CD69 on subsets of thymocytes suggests that it may be involved in regulation of developmental events in addition to its role in activation of a variety of hematopoietic cells.