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CD80 anticorps

CD80 Reactivité: Souris FACS Hôte: Rat Monoclonal 1G10 unconjugated
N° du produit ABIN135268
  • Antigène Voir toutes CD80 Anticorps
    CD80
    Reactivité
    • 148
    • 114
    • 46
    • 8
    • 3
    • 3
    • 1
    • 1
    • 1
    Souris
    Hôte
    • 92
    • 77
    • 23
    • 22
    • 20
    • 1
    • 1
    Rat
    Clonalité
    • 151
    • 82
    • 2
    Monoclonal
    Conjugué
    • 90
    • 21
    • 20
    • 17
    • 14
    • 5
    • 4
    • 4
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    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD80 est non-conjugé
    Application
    • 140
    • 95
    • 69
    • 39
    • 36
    • 23
    • 14
    • 13
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    • 13
    • 11
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    Flow Cytometry (FACS)
    Specificité
    Mouse CD80, Mr 52-55 kDa
    Attributs du produit
    Rat Anti-Mouse CD80-UNLB
    Purification
    Purified
    Immunogène
    Activated 5C2 cells
    Clone
    1G10
    Isotype
    IgG2a
    Top Product
    Discover our top product CD80 Anticorps primaire
  • Indications d'application
    • Applications: FC - Quality tested , IP - Reported in literature , Block - Reported in literature
    • Working Dilutions: Flow Cytometry FITC and BIOT conjugates 1 g/106 cells PE, APC, and SPRD conjugates 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
    Commentaires

    In vivo and in vitro blocking of ligand binding

    Volume d'échantillon
    1 mL
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    0.5 mg of purified immunoglobulin in 1.0 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added
    Agent conservateur
    Without preservative
    Conseil sur la manipulation
    Each reagent is stable for the period shown on the bottle label if stored as directed.
    Stock
    4 °C
    Stockage commentaire
    Store at 2-8°C
  • Antigène
    CD80
    Autre désignation
    CD80 (CD80 Produits)
    Synonymes
    anticorps B7, anticorps B7-1, anticorps B7.1, anticorps BB1, anticorps CD28LG, anticorps CD28LG1, anticorps LAB7, anticorps B71, anticorps Cd28l, anticorps Ly-53, anticorps Ly53, anticorps MIC17, anticorps TSA1, anticorps CD80 molecule, anticorps Cd80 molecule, anticorps CD80 antigen, anticorps CD80, anticorps Cd80
    Sujet
    CD80 (B7-1) is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is constitutively expressed by dendritic cells, monocytes, and peritoneal macrophages. Expression of CD80 on B cells is upregulated after activation by various means including stimulation by LPS, IL-4, and surface Ig receptor cross linking with peak expression occurring between 48 and 72 hours post-activation. The interaction of CD80/B7-1 with its ligands, CD28 and CD152/CTLA-4, provides a potent costimulatory signal for T cells activated through the CD3/T cell receptor complex.
    Pathways
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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