CD80 anticorps
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- Antigène Voir toutes CD80 Anticorps
- CD80
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Reactivité
- Souris
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Hôte
- Rat
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD80 est non-conjugé
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Application
- Flow Cytometry (FACS)
- Specificité
- Mouse CD80, Mr 52-55 kDa
- Attributs du produit
- Rat Anti-Mouse CD80-LE/AF
- Purification
- Ion exchange
- niveau d'endotoxine
- Low endotoxin
- Immunogène
- Activated 5C2 cells
- Clone
- 1G10
- Isotype
- IgG2a
- Top Product
- Discover our top product CD80 Anticorps primaire
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- Indications d'application
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- Applications: FC - Quality tested , IP - Reported in literature , Block - Reported in literature
- Working Dilutions: Flow Cytometry FITC and BIOT conjugates 1 g/106 cells PE, APC, and SPRD conjugates 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
- Commentaires
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In vivo and in vitro blocking of ligand binding
- Volume d'échantillon
- 1 mL
- Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- 0.5 mg of purified immunoglobulin in 1.0 mL of PBS
- Agent conservateur
- Azide free
- Conseil sur la manipulation
- Each reagent is stable for the period shown on the bottle label if stored as directed.
- Stock
- -20 °C
- Stockage commentaire
- Aliquot and freeze the low endotoxin, azide-free product at -20 °C immediately upon receipt.
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- Antigène
- CD80
- Autre désignation
- CD80 (CD80 Produits)
- Synonymes
- anticorps B7, anticorps B7-1, anticorps B7.1, anticorps BB1, anticorps CD28LG, anticorps CD28LG1, anticorps LAB7, anticorps B71, anticorps Cd28l, anticorps Ly-53, anticorps Ly53, anticorps MIC17, anticorps TSA1, anticorps CD80 molecule, anticorps Cd80 molecule, anticorps CD80 antigen, anticorps CD80, anticorps Cd80
- Sujet
- CD80 (B7-1) is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is constitutively expressed by dendritic cells, monocytes, and peritoneal macrophages. Expression of CD80 on B cells is upregulated after activation by various means including stimulation by LPS, IL-4, and surface Ig receptor cross linking with peak expression occurring between 48 and 72 hours post-activation. The interaction of CD80/B7-1 with its ligands, CD28 and CD152/CTLA-4, provides a potent costimulatory signal for T cells activated through the CD3/T cell receptor complex.
- Pathways
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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