CTLA4 anticorps
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- Antigène Voir toutes CTLA4 Anticorps
- CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
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Reactivité
- Souris
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Hôte
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Hamster
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CTLA4 est non-conjugé
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Application
- ELISA
- Specificité
- Mouse CD152, Mr 33-37 kDa
- Attributs du produit
- Hamster Anti-Mouse CD152-UNLB
- Purification
- Purified
- Immunogène
- Extracellular portion of murine CTLA-4 fused to a murine IgG2a
- Clone
- 1B8
- Isotype
- IgG
- Top Product
- Discover our top product CTLA4 Anticorps primaire
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- Indications d'application
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- Applications: ELISA - Quality tested , FLISA - Quality tested FC - Reported literature , Stim - Reported in literature
- Working Dilutions: ELISA BIOT conjugate 1:5,000 - 1:10,000 FLISA FITC conjugate 1:100 - 1:400 PE conjugate 1 g/mL Flow Cytometry FITC and BIOT conjugates 3 g/106 cells PE conjugate 0.3 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
- Commentaires
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In vitro functional studies
- Volume d'échantillon
- 1 mL
- Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- 0.5 mg of purified immunoglobulin in 1.0 mL of borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added
- Agent conservateur
- Without preservative
- Conseil sur la manipulation
- Each reagent is stable for the period shown on the bottle label if stored as directed.
- Stock
- 4 °C
- Stockage commentaire
- Store at 2-8°C
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- Antigène
- CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
- Autre désignation
- CD152 (CTLA4 Produits)
- Sujet
- The lymphocyte surface antigen CD152, also known as CTLA-4, is related to the co-stimulatory molecule CD28, and both molecules share common B7 family counter-receptors. However CD152 is thought to be a negative regulator of T cell activation and may play a role in apoptotic control of T cells. CD152 exists as a 69 kDa homodimer, and is relatively conserved among humans, mice and chickens.
- Pathways
- Cancer Immune Checkpoints
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