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CTLA4 anticorps

CTLA4 Reactivité: Souris ELISA Hôte: Hamster Monoclonal 1B8 unconjugated
N° du produit ABIN135313
  • Antigène Voir toutes CTLA4 Anticorps
    CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
    Reactivité
    • 114
    • 75
    • 33
    • 4
    • 3
    Souris
    Hôte
    • 71
    • 60
    • 22
    • 12
    • 1
    • 1
    • 1
    Hamster
    Clonalité
    • 102
    • 62
    • 3
    Monoclonal
    Conjugué
    • 77
    • 17
    • 13
    • 12
    • 8
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CTLA4 est non-conjugé
    Application
    • 98
    • 64
    • 57
    • 32
    • 22
    • 17
    • 13
    • 12
    • 10
    • 8
    • 8
    • 6
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA
    Specificité
    Mouse CD152, Mr 33-37 kDa
    Attributs du produit
    Hamster Anti-Mouse CD152-UNLB
    Purification
    Purified
    Immunogène
    Extracellular portion of murine CTLA-4 fused to a murine IgG2a
    Clone
    1B8
    Isotype
    IgG
    Top Product
    Discover our top product CTLA4 Anticorps primaire
  • Indications d'application
    • Applications: ELISA - Quality tested , FLISA - Quality tested FC - Reported literature , Stim - Reported in literature
    • Working Dilutions: ELISA BIOT conjugate 1:5,000 - 1:10,000 FLISA FITC conjugate 1:100 - 1:400 PE conjugate 1 g/mL Flow Cytometry FITC and BIOT conjugates 3 g/106 cells PE conjugate 0.3 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
    Commentaires

    In vitro functional studies

    Volume d'échantillon
    1 mL
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    0.5 mg of purified immunoglobulin in 1.0 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added
    Agent conservateur
    Without preservative
    Conseil sur la manipulation
    Each reagent is stable for the period shown on the bottle label if stored as directed.
    Stock
    4 °C
    Stockage commentaire
    Store at 2-8°C
  • Antigène
    CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
    Autre désignation
    CD152 (CTLA4 Produits)
    Sujet
    The lymphocyte surface antigen CD152, also known as CTLA-4, is related to the co-stimulatory molecule CD28, and both molecules share common B7 family counter-receptors. However CD152 is thought to be a negative regulator of T cell activation and may play a role in apoptotic control of T cells. CD152 exists as a 69 kDa homodimer, and is relatively conserved among humans, mice and chickens.
    Pathways
    Cancer Immune Checkpoints
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