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CD45.1 anticorps (Biotin)

Reactivité: Souris FACS Hôte: Souris Monoclonal A20 Biotin
N° du produit ABIN135322
  • Antigène Tous les produits CD45.1
    CD45.1 (CD45 (CD45.1 Allogen))
    Reactivité
    Souris
    Hôte
    • 57
    Souris
    Clonalité
    • 57
    Monoclonal
    Conjugué
    • 7
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD45.1 est conjugé à/à la Biotin
    Application
    • 52
    • 14
    • 13
    • 11
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Specificité
    Mouse CD45.1, Mr 180-240 kDa
    Attributs du produit
    Mouse Anti-Mouse CD45.1-BIOT
    Immunogène
    SJL mouse thymocytes and splenocytes
    Clone
    A20
    Isotype
    IgG2a
  • Indications d'application
    • Applications: FC - Quality tested , IHC-FS - Reported in literature , IHC-PS - Reported in literature
    • Working Dilutions: Flow Cytometry FITC, BIOT, and AF488 conjugates 1 g/106 cells PACBLU conjugate 0.3 g/106 cells PE, APC, SPRD, CY5, PE/CY5.5, PE/CY7, APC/CY5.5, 0.2 g/106 cells APC/CY7, and AF647 conjugates For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
    Volume d'échantillon
    1 mL
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    0.5 mg in 1.0 mL of PBS/Sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Protect conjugated products from light.
    Each reagent is stable for the period shown on the bottle label if stored as directed.
    Stock
    4 °C
    Stockage commentaire
    Store at 2-8°C
  • Antigène
    CD45.1 (CD45 (CD45.1 Allogen))
    Autre désignation
    CD45.1 (CD45.1 Produits)
    Sujet
    The CD45 antigen is an essential regulator of leukocyte activation and development, and is now known to be a protein tyrosine phosphatase, e.g. CD45 is able to dephosphorylate the Src family of protein kinases. This activity is now known to be required for signal transduction induced by T and B cell antigen receptor engagement, cytokine signaling and Fc receptor stimulation. The functional state of CD45 also has a pronounced effect on lymphocyte development. CD45 exists in multiple forms, such as the restricted variants (CD45R) and as allelic forms CD45.1/Ly-5.1 and CD45.2/Ly-5.2. The former arises as a result of alternative splicing of different exons. The specificity of antibodies to CD45.1 and CD45.2 has been exploited in studies where resolution of donor and recipient cells is essential, such as in gene therapy or bone marrow transplantation.
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