NK-1.1/CD161c anticorps
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- Antigène Tous les produits NK-1.1/CD161c
- NK-1.1/CD161c (NK-1.1)
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Reactivité
- Souris
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp NK-1.1/CD161c est non-conjugé
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Application
- Flow Cytometry (FACS)
- Specificité
- Mouse NK1.1, Mr 39 kDa
- Attributs du produit
- Mouse Anti-Mouse NK1.1-LE/AF
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
- niveau d'endotoxine
- Low endotoxin
- Immunogène
- CE mouse spleen enriched for NK-1+ cells and bone marrow cells
- Clone
- PK136
- Isotype
- IgG2a
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- Indications d'application
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- Applications: FC - Quality tested , IHC - Reported in literature , IP - Reported in literature , Depletion - Reported in literature , CMCD - Reported in literature , Block - Reported in literature , Activ - Reported in literature
- Working Dilutions: Flow Cytometry FITC, BIOT, PACBLU, AF488, and AF700 conjugates 1 g/106 cells PE and APC conjugates 0.5 g/106 cells PE/CY7 and AF647 conjugates 0.3 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
- Commentaires
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Induction of proliferation of a subset of NK cells, In vivo depletion of NK1.1 cells, In vitro redirected lysis, In vitro cytotoxicity assays
- Volume d'échantillon
- 1 mL
- Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- 0.5 mg of purified immunoglobulin in 1.0 mL of PBS
- Agent conservateur
- Azide free
- Conseil sur la manipulation
- Each reagent is stable for the period shown on the bottle label if stored as directed.
- Stock
- -20 °C
- Stockage commentaire
- Aliquot and freeze the low endotoxin, azide-free product at -20 °C immediately upon receipt.
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- Antigène
- NK-1.1/CD161c (NK-1.1)
- Autre désignation
- NK1.1 (NK-1.1/CD161c Produits)
- Synonymes
- anticorps AI462337, anticorps CD161, anticorps Ly-59, anticorps Ly55c, anticorps Ly59, anticorps NK-RP1, anticorps NK1.1, anticorps NKR-P1.9, anticorps NKRP1, anticorps NKRP140, anticorps Nk-1, anticorps Nk-1.2, anticorps Nk1, anticorps Nk1.2, anticorps Nkrp1c, anticorps ly-55c, anticorps killer cell lectin-like receptor subfamily B member 1C, anticorps Klrb1c
- Sujet
- NK1.1, a member of the NKR-P1 family of cell surface receptors, is a type II integral membrane glycoprotein with a C-type lectin domain. It is expressed as a disulfide-linked homodimer on all NK cells, as well as subsets of thymocytes and peripheral T lymphocytes in selected strains of mice (e.g., C57BL, NZB). NK1.1 mediates cellular activation and differentiation, and is thought to have a particular role in generating Th2 cells. This product does not react with NK cells of BALB/c mice.
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