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NK-1.1/CD161c anticorps

Reactivité: Souris FACS Hôte: Souris Monoclonal PK136 unconjugated
N° du produit ABIN135344
  • Antigène Tous les produits NK-1.1/CD161c
    NK-1.1/CD161c (NK-1.1)
    Reactivité
    • 64
    • 16
    • 1
    Souris
    Hôte
    • 47
    • 17
    • 1
    Souris
    Clonalité
    • 47
    • 16
    • 2
    Monoclonal
    Conjugué
    • 12
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    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
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    Cet anticorp NK-1.1/CD161c est non-conjugé
    Application
    • 56
    • 17
    • 13
    • 11
    • 6
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    • 5
    • 5
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    • 3
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    Flow Cytometry (FACS)
    Specificité
    Mouse NK1.1, Mr 39 kDa
    Attributs du produit
    Mouse Anti-Mouse NK1.1-LE/AF
    Purification
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
    niveau d'endotoxine
    Low endotoxin
    Immunogène
    CE mouse spleen enriched for NK-1+ cells and bone marrow cells
    Clone
    PK136
    Isotype
    IgG2a
  • Indications d'application
    • Applications: FC - Quality tested , IHC - Reported in literature , IP - Reported in literature , Depletion - Reported in literature , CMCD - Reported in literature , Block - Reported in literature , Activ - Reported in literature
    • Working Dilutions: Flow Cytometry FITC, BIOT, PACBLU, AF488, and AF700 conjugates 1 g/106 cells PE and APC conjugates 0.5 g/106 cells PE/CY7 and AF647 conjugates 0.3 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
    Commentaires

    Induction of proliferation of a subset of NK cells, In vivo depletion of NK1.1 cells, In vitro redirected lysis, In vitro cytotoxicity assays

    Volume d'échantillon
    1 mL
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    0.5 mg of purified immunoglobulin in 1.0 mL of PBS
    Agent conservateur
    Azide free
    Conseil sur la manipulation
    Each reagent is stable for the period shown on the bottle label if stored as directed.
    Stock
    -20 °C
    Stockage commentaire
    Aliquot and freeze the low endotoxin, azide-free product at -20 °C immediately upon receipt.
  • Antigène
    NK-1.1/CD161c (NK-1.1)
    Autre désignation
    NK1.1 (NK-1.1/CD161c Produits)
    Synonymes
    anticorps AI462337, anticorps CD161, anticorps Ly-59, anticorps Ly55c, anticorps Ly59, anticorps NK-RP1, anticorps NK1.1, anticorps NKR-P1.9, anticorps NKRP1, anticorps NKRP140, anticorps Nk-1, anticorps Nk-1.2, anticorps Nk1, anticorps Nk1.2, anticorps Nkrp1c, anticorps ly-55c, anticorps killer cell lectin-like receptor subfamily B member 1C, anticorps Klrb1c
    Sujet
    NK1.1, a member of the NKR-P1 family of cell surface receptors, is a type II integral membrane glycoprotein with a C-type lectin domain. It is expressed as a disulfide-linked homodimer on all NK cells, as well as subsets of thymocytes and peripheral T lymphocytes in selected strains of mice (e.g., C57BL, NZB). NK1.1 mediates cellular activation and differentiation, and is thought to have a particular role in generating Th2 cells. This product does not react with NK cells of BALB/c mice.
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