CD24 anticorps
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- Antigène Voir toutes CD24 Anticorps
- CD24 (CD24 Molecule (CD24))
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Reactivité
- Souris
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Hôte
- Rat
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD24 est non-conjugé
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Application
- Flow Cytometry (FACS)
- Specificité
- Mouse CD24, Mr 35-45 kDa
- Attributs du produit
- Rat Anti-Mouse CD24-UNLB
- Purification
- Purified
- Immunogène
- Mouse thymus or spleen
- Clone
- 30-F1
- Isotype
- IgG2c
- Top Product
- Discover our top product CD24 Anticorps primaire
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- Indications d'application
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- Applications: FC - Quality tested
- Working Dilutions: Flow Cytometry FITC and BIOT conjugates 2 g/106 cells PE, APC, and SPRD conjugates 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
- Volume d'échantillon
- 1 mL
- Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- 0.5 mg of purified immunoglobulin in 1.0 mL of borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added
- Agent conservateur
- Without preservative
- Conseil sur la manipulation
- Each reagent is stable for the period shown on the bottle label if stored as directed.
- Stock
- 4 °C
- Stockage commentaire
- Store at 2-8°C
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- Antigène
- CD24 (CD24 Molecule (CD24))
- Autre désignation
- CD24 (CD24 Produits)
- Synonymes
- anticorps CD24A, anticorps Cd24a, anticorps CD24 molecule, anticorps CD24, anticorps Cd24
- Sujet
- CD24 is expressed in B cells until their terminal differentiation into plasma cells. It has been used widely as a marker to fractionate different B-lineage differentiation stages. CD24 has been found on a variety of other hematopoietic and neural cell types, and is now classified as a costimulatory molecule. The CD24/HSA molecule is composed mostly of carbohydrate, with a protein core of only 31-35 amino acids in the human and 27 AA in the mouse. The molecular mass is variable, ranging from 38-70 kDa. CD24 is now included in the large group of phosphatidylinositol-anchored membrane proteins. Studies with purified CD24 applied to latex beads have demonstrated a self-binding property, suggesting that the molecule is capable of promoting homotypic aggregation, binding and cell adhesion. This is supported by earlier observations of the blockade of B cell lymphoblast aggregation with anti-CD24 monoclonal antibody. Recent studies of murine CD24 have assigned a role for CD24/HSA as a ligand for P-selectin, a calcium-dependent lectin.
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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