BAD anticorps (pSer155)
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- Antigène Voir toutes BAD Anticorps
- BAD (BCL2-Associated Agonist of Cell Death (BAD))
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Épitope
- pSer155
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp BAD est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Specificité
- The antibody detects endogenous level of BAD only when phosphorylated at serine 155.
- Immunogène
- Peptide sequence around phosphorylation site of pSer155 (R-M-S (p) -D-E) derived from Human BAD. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
- Top Product
- Discover our top product BAD Anticorps primaire
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- Indications d'application
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Western blotting: 1:500
Immunohistochemistry: 1:50-1:100 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store at -20 °C
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- Antigène
- BAD (BCL2-Associated Agonist of Cell Death (BAD))
- Autre désignation
- BAD (BAD Produits)
- Synonymes
- anticorps bad, anticorps fa01b12, anticorps wu:fa01b12, anticorps wu:fa96d04, anticorps BAD, anticorps BBC2, anticorps BCL2L8, anticorps AI325008, anticorps Bbc2, anticorps BCL2-associated agonist of cell death b, anticorps BCL2 associated agonist of cell death, anticorps BCL2-associated agonist of cell death, anticorps badb, anticorps BAD, anticorps Bad
- Sujet
- Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2. Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.
- Poids moléculaire
- 23 kDa
- NCBI Accession
- NM_007522, NP_031548
- UniProt
- Q61337
- Pathways
- Signalisation MAPK, Signalisation PI3K-Akt, Signalisation RTK, Apoptose, Fc-epsilon Receptor Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Hepatitis C, CXCR4-mediated Signaling Events
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