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Ezrin anticorps (pTyr353)

EZR Reactivité: Humain, Souris WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1355834
  • Antigène Voir toutes Ezrin (EZR) Anticorps
    Ezrin (EZR)
    Épitope
    • 29
    • 16
    • 12
    • 11
    • 9
    • 9
    • 8
    • 8
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr353
    Reactivité
    • 154
    • 82
    • 74
    • 8
    • 7
    • 7
    • 6
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 140
    • 13
    • 3
    • 2
    Lapin
    Clonalité
    • 137
    • 20
    Polyclonal
    Conjugué
    • 89
    • 8
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Cet anticorp Ezrin est non-conjugé
    Application
    • 117
    • 54
    • 27
    • 16
    • 14
    • 14
    • 13
    • 13
    • 10
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Specificité
    The antibody detects endogenous level of Ezrin only when phosphorylated at tyrosine 353.
    Immunogène
    Peptide sequence around phosphorylation site of pTyr353 (Q-D-Y (p) -E-E) derived from Human EZRIN. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
    Top Product
    Discover our top product EZR Anticorps primaire
  • Indications d'application
    Western blotting: 1:500-1:1000
    Immunohistochemistry: 1:50-1:100  
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • Oda, Aishima, Morimatsu, Hayashi, Shindo, Fujino, Mizuuchi, Hattori, Tanaka, Oda: "Differential ezrin and phosphorylated ezrin expression profiles between pancreatic intraepithelial neoplasia, intraductal papillary mucinous neoplasm, and invasive ductal carcinoma of the pancreas." dans: Human pathology, Vol. 44, Issue 8, pp. 1487-98, (2013) (PubMed).

    Morimatsu, Aishima, Kayashima, Hayashi, Nakata, Oda, Taguchi, Tsuneyoshi, Tanaka, Oda: "Liver-intestine cadherin expression is associated with intestinal differentiation and carcinogenesis in intraductal papillary mucinous neoplasm." dans: Pathobiology : journal of immunopathology, molecular and cellular biology, Vol. 79, Issue 2, pp. 107-14, (2012) (PubMed).

    Cui, Li, Zhang, Han: "Expression of Ezrin and phosphorylated Ezrin (pEzrin) in pancreatic ductal adenocarcinoma." dans: Cancer investigation, Vol. 28, Issue 3, pp. 242-7, (2010) (PubMed).

  • Antigène
    Ezrin (EZR)
    Autre désignation
    Ezrin (EZR Produits)
    Synonymes
    anticorps CVIL, anticorps CVL, anticorps VIL2, anticorps ezr, anticorps vil2, anticorps wu:fc05c03, anticorps wu:fj31d06, anticorps cvil, anticorps cvl, anticorps Vil2, anticorps AW146364, anticorps R75297, anticorps p81, anticorps ezr.S, anticorps ezrin, anticorps ezrin b, anticorps ezrin L homeolog, anticorps EZR, anticorps ezrb, anticorps ezr, anticorps Ezr, anticorps ezr.L
    Sujet
    Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis.
    Poids moléculaire
    81 kDa
    NCBI Accession
    NP_001104
    UniProt
    P15311
    Pathways
    Maintenance of Protein Location
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