CD35 anticorps

N° du produit ABIN135765

Détail du produit anti-CD35 anticorps

Antigène: CD35 (CR1) (Complement Component Receptor 1 (CD35) (CR1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD35 est non-conjugé

Application: Flow Cytometry (FACS), DNA Microscopy (DNA Mic)

Specificité: Human/Rhesus/Cynomolgus/Chimpanzee/Baboon CD35, Mr 160, 190, 220, 250 kDa

Attributs du produit: Mouse Anti-Human CD35-UNLB

Purification: Purified

Immunogène: Acute monocytic leukemia cells and normal blood monocytes

Clone: E11

Isotype: IgG1

Information d'application

Indications d'application:

• Applications: FC - Quality tested , IHC-FS - Reported in literature , IHC-PS - Reported in literature , IP - Reported in literature , WB - Reported in literature , ELISA - Reported in literature
• Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells FITC and PE conjugate 10 L/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

Volume d'échantillon: 1 mL

Restrictions: For Research Use only

Stockage

Concentration: 0.1 mg/mL

Buffer: 0.1 mg of purified immunoglobulin in 1.0 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added

Agent conservateur: Without preservative

Conseil sur la manipulation: Each reagent is stable for the period shown on the bottle label if stored as directed.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C

Références pour anticorps anti-CD35 (ABIN135765)

Avanzi, Leoni, Rotola, Alviano, Solimando, Lanzoni, Bonsi, Di Luca, Marchionni, Alvisi, Ripalti: "Susceptibility of human placenta derived mesenchymal stromal/stem cells to human herpesviruses infection." dans: PLoS ONE, Vol. 8, Issue 8, pp. e71412, (2013) (PubMed).

Détails sur CD35

Antigène: CD35 (CR1) (Complement Component Receptor 1 (CD35) (CR1))

Autre désignation: CD35 (CR1 Produits)

Synonymes: anticorps C3BR, anticorps C4BR, anticorps CD35, anticorps KN, anticorps C3DR, anticorps CD21, anticorps Cr-1, anticorps Cr-2, anticorps Cr1, anticorps CR1-L, anticorps CR2, anticorps CR1, anticorps complement C3b/C4b receptor 1 (Knops blood group), anticorps complement receptor 2, anticorps complement component (3d/Epstein Barr virus) receptor 2, anticorps complement receptor type 1, anticorps CR1, anticorps Cr2, anticorps CR2, anticorps LOC718120

Sujet: The CD35 antigen is composed of four different allotypes having different molecular weights (A (or F) - 160 kDa, B (or S) - 190 kDa, C - 220 kDa, and D - 250 kDa). It is the receptor for C3b and is found on B cells, a subset of T cells, monocytes, neutrophils, follicular dendritic cells, erythrocytes and kidney glomelular podocytes. CD35 mediates neutrophil and monocyte phagocytosis of particles coated with C3b and/or C4b. This interaction also enhances phagocytosis mediated by the Fc receptors.

Pathways: Système du Complément, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Endopeptidase Activity