CD40 anticorps
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- Antigène Voir toutes CD40 Anticorps
- CD40
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD40 est non-conjugé
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Application
- Flow Cytometry (FACS), Immunohistochemistry (IHC), Functional Studies (Func)
- Specificité
- Recognises the Bp50 antigen, a 48 kDa protein
- Purification
- Ion exchange chromatography
- Stérilité
- 0.22 μm filtered
- Immunogène
- Raji cell line,Myeloma X63/AG.8653 x Balb/c spleen cells
- Clone
- B-B20
- Isotype
- IgG1 kappa
- Biological Activity Comment
- Stimulates B-cell proliferation together with IL-4
- Top Product
- Discover our top product CD40 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Phosphate-buffered saline. Sterile-filtered through 0.22 μm. Carrier and preservative free
- Agent conservateur
- Without preservative
- Stock
- 4 °C
- Stockage commentaire
- Stable at +2-8°C for 12 months. For longer storage freeze aliquots.
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Differential effect of agonistic anti-CD40 on human mature and immature dendritic cells: the Janus face of anti-CD40." dans: Blood, Vol. 106, Issue 8, pp. 2806-14, (2005) (PubMed).
: "In human B cells, IL-12 triggers a cascade of molecular events similar to Th1 commitment." dans: Blood, Vol. 102, Issue 12, pp. 4084-9, (2003) (PubMed).
: "Extracellular signal-regulated protein kinase signaling pathway negatively regulates the phenotypic and functional maturation of monocyte-derived human dendritic cells." dans: Blood, Vol. 98, Issue 7, pp. 2175-82, (2001) (PubMed).
: "CD86 (B7-2) on human B cells. A functional role in proliferation and selective differentiation into IgE- and IgG4-producing cells." dans: The Journal of biological chemistry, Vol. 272, Issue 25, pp. 15613-9, (1997) (PubMed).
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Differential effect of agonistic anti-CD40 on human mature and immature dendritic cells: the Janus face of anti-CD40." dans: Blood, Vol. 106, Issue 8, pp. 2806-14, (2005) (PubMed).
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- Antigène
- CD40
- Autre désignation
- CD40 (CD40 Produits)
- Synonymes
- anticorps Bp50, anticorps CDW40, anticorps TNFRSF5, anticorps p50, anticorps AI326936, anticorps GP39, anticorps HIGM1, anticorps IGM, anticorps IMD3, anticorps T-BAM, anticorps TRAP, anticorps Tnfrsf5, anticorps TNFSF5, anticorps CD40 molecule, anticorps CD40 antigen, anticorps CD40, anticorps Cd40
- Poids moléculaire
- 48 kDa
- Pathways
- Signalisation NF-kappaB, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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