Complement C4 anticorps (AA 701-800)

N° du produit ABIN1385186

Détail du produit anti-Complement C4 anticorps

Antigène: Complement C4 (C4) (Complement 4 (C4))

Épitope: AA 701-800

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Complement C4 est non-conjugé

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: Human

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Complement C4 C4a anaphylatoxin or complement C4 alpha chain

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur Complement C4

Antigène: Complement C4 (C4) (Complement 4 (C4))

Autre désignation: Complement C4/C4 (C4 Produits)

Synonymes: anticorps C4B1, anticorps C4B12, anticorps C4B2, anticorps C4B3, anticorps C4B5, anticorps C4BD, anticorps C4B_2, anticorps C4F, anticorps CH, anticorps CO4, anticorps CPAMD3, anticorps C4, anticorps C4A2, anticorps C4A3, anticorps C4A4, anticorps C4A6, anticorps C4AD, anticorps C4S, anticorps CPAMD2, anticorps RG, anticorps C4-1, anticorps C4b, anticorps C4-2, anticorps Slp, anticorps Ss, anticorps complement C4B (Chido blood group), anticorps complement C4A (Rodgers blood group), anticorps complement component 4A (Rodgers blood group), anticorps complement 4, anticorps complement component 4A, anticorps complement component 4B (Chido blood group), anticorps C4B, anticorps C4A, anticorps C4a, anticorps C4, anticorps C4b

Sujet:

Synonyms: C4a anaphylatoxin, Complement C4-A alpha chain, complement C4-A proprotein, Acidic C4, Acidic complement C4, Basic C4, Basic complement C4, C4 Anaphylatoxin, C4 complement C4d region, complement C4 alpha chain, C4A, C4A13, C4A2, C4A3, C4A4, C4A6, C4A91, C4B, C4B1, C4B12, C4B2, C4B3, C4B5, C4F, C4S, CH, Chido form of C4, CO4, Complement C4 A, Complement C4 B, Complement C4B, Complement component 4A Rodgers blood group, Complement component 4A, Complement component 4B Childo blood group, Complement component 4B, Complement component C4B, CPAMD2, CPAMD3. RG, Rodgers Form Of C4.

Background: This gene encodes the acidic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus and type I diabetes mellitus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011].

ID gène: 720, 721

Pathways: Système du Complément