UBR2 anticorps
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- Antigène Voir toutes UBR2 Anticorps
- UBR2 (Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp UBR2 est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Réactivité croisée
- Humain, Souris, Rat
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human UBR2
- Isotype
- IgG
- Top Product
- Discover our top product UBR2 Anticorps primaire
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- Indications d'application
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WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- UBR2 (Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2))
- Autre désignation
- UBR2 (UBR2 Produits)
- Synonymes
- anticorps ba49a4.1, anticorps si:ch211-239i4.2, anticorps C6orf133, anticorps RP3-392M17.3, anticorps bA49A4.1, anticorps dJ242G1.1, anticorps dJ392M17.3, anticorps 9930021A08Rik, anticorps AI462103, anticorps AW540746, anticorps E130209G04Rik, anticorps mKIAA0349, anticorps ubiquitin protein ligase E3 component n-recognin 2, anticorps ubiquitin protein ligase E3 component n-recognin 2 S homeolog, anticorps UBR2, anticorps ubr2, anticorps ubr2.S, anticorps Ubr2
- Sujet
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Synonyms: E3 ubiquitin protein ligase UBR2, N recognin 2, Ubiquitin ligase E3 alpha II, Ubiquitin protein ligase E3 alpha 2, Ubiquitin protein ligase E3 component n recognin 2, UBR 2, UBR2_HUMAN, N-recognin-2, Ubiquitin-protein ligase E3-alpha-2, Ubiquitin-protein ligase E3-alpha-II.
Background: Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). Ubr2 (Ubiquitin-protein ligase E3-alpha-2), also known as N-recognin-2, is a 1755 amino acid protein that contains one UBR-type zinc finger and one RING-type zinc finger. Participating in protein modification events within the N-end rule pathway, Ubr2 functions as an E3 ubiquitin-protein ligase that recognizes and binds proteins that contain destabilizing N-terminal residues, thereby leading to their ubiquitination and subsequent degradation. Mice lacking Ubr2 are infertile due to defects in male meiosis.
- ID gène
- 23304
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