PGBD3 anticorps (AA 410-460)

N° du produit ABIN1385394

Détail du produit anti-PGBD3 anticorps

Antigène: PGBD3 (PiggyBac Transposable Element Derived 3 (PGBD3))

Épitope: AA 410-460

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PGBD3 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human PGBD3

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur PGBD3

Antigène: PGBD3 (PiggyBac Transposable Element Derived 3 (PGBD3))

Autre désignation: PGBD3 (PGBD3 Produits)

Synonymes: anticorps PGBD3, anticorps piggyBac transposable element derived 3, anticorps ERCC excision repair 6, chromatin remodeling factor, anticorps PGBD3, anticorps ERCC6

Sujet:

Synonyms: PGBD 3, PiggyBac transposable element derived 3, PiggyBac transposable element derived protein 3, PGBD3_HUMAN.

Background: PiggyBac transposable element derived 3, also known as PGBD3, encodes a 593 amino acid transposase and is a member of the piggyBac transposable element derived (PGBD) gene family, which includes several genes that are derived from piggyBac transposons. Initially characterized in the cabbacge looper moth, Trichoplusia ni, the PGBD family is conserved in a wide variety of species, including protozoa and primates. More specifically, while PGBD3 and PGBD4 are primate-specific genes, the other three members of the PGBD family (namely PGBD1, PGBD2 and PGBD5) are conserved among a variety of vertebrates. PGBD3 appears to be novel, with no clear relationship to other transposases or other known protein families. However, the PGBD3 gene overlaps with the CSB gene on chromosome 10 and, with the CSB gene, plays a role in Cockayne syndrome, a rare disorder characterized by premature aging, microcephaly, photosensitivity and severe neurologic degeneration.

ID gène: 267004

UniProt: Q8N328

Pathways: Chromatin Binding