TSPAN10 anticorps

N° du produit ABIN1385407

Détail du produit anti-TSPAN10 anticorps

Antigène: TSPAN10 (Tetraspanin 10 (TSPAN10))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TSPAN10 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human TSPAN10/Oculospanin

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur TSPAN10

Antigène: TSPAN10 (Tetraspanin 10 (TSPAN10))

Autre désignation: TSPAN10 (TSPAN10 Produits)

Synonymes: anticorps GB13074, anticorps OCSP, anticorps Ocsp, anticorps tetraspanin 10, anticorps tetraspanin-10, anticorps Tspan10, anticorps TSPAN10, anticorps LOC483364

Sujet:

Synonyms: OCSP, oculospanin, tetraspanin 10, Tspan 10, TSN10_HUMAN.

Background: The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. Oculospanin, also known as tetraspanin 10 (TSPAN10) or OCSP, is a 355 amino acid multi-pass membrane protein belonging to the tetraspanin (TM4SF) family. Oculospanin is expressed in certain regions of the eye such as retinal pigment epithelium, ciliary body and iris, but is not found in the lens. The gene encoding Oculospanin maps to human chromosome 17, which comprises over 2.5 % of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, and is liked to predisposition of cancers of the ovary, colon, prostate gland and fallopian tubes.

ID gène: 83882