ANKRD20A3 anticorps

N° du produit ABIN1385483

Détail du produit anti-ANKRD20A3 anticorps

Antigène: ANKRD20A3 (Ankyrin Repeat Domain 20 Family, Member A3 (ANKRD20A3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ANKRD20A3 est non-conjugé

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human ANKRD20A3

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur ANKRD20A3

Antigène: ANKRD20A3 (Ankyrin Repeat Domain 20 Family, Member A3 (ANKRD20A3))

Autre désignation: ANKRD20A3 (ANKRD20A3 Produits)

Synonymes: anticorps ankyrin repeat domain 20 family member A3, anticorps ANKRD20A3

Sujet:

Synonyms: Ankyrin repeat domain 20 family member A3, Ankyrin repeat domain 20A related, Ankyrin repeat domain containing protein 20A3, MGC176486, MGC198508, A20A3_HUMAN.

Background: Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. Mutations of ankyrin genes lead to severe genetic diseases such as fatal cardiac arrhythmias and hereditary spherocytosis. ANKRD20A (ankyrin repeat domain-containing protein 20A) is an 823 amino acid protein that contains five ANK repeats. The gene encoding ANKRD20A maps to chromosome 9, which consists of about 145 million bases and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and familial dysautonomia are associated with chromosome 9. Also, chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias.

ID gène: 441425