HIV-1 Gag anticorps (AA 351-450)

N° du produit ABIN1385564

Détail du produit anti-HIV-1 Gag anticorps

Antigène: HIV-1 Gag (GAG_HIV) (HIV-1 Gag Polyprotein (GAG_HIV))

Épitope: AA 351-450

Reactivité: Human Immunodeficiency Virus (HIV), Virus

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HIV-1 Gag est non-conjugé

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody will recognize the full Gag protein and Nucleocapsid protein p7 after cleavage

Réactivité croisée: Virus

Réactivité croisée (Details): HIV

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from HIV1 Nucleocapsid protein p7

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur HIV-1 Gag

Antigène: HIV-1 Gag (GAG_HIV) (HIV-1 Gag Polyprotein (GAG_HIV))

Autre désignation: HIV1 Gag Protein (GAG_HIV Produits)

Classe de substances: Viral Protein

Sujet:

Synonyms: HIV1 Pr55Gag, Human immunodeficiency virus 1, Gag protein, Nucleocapsid protein p7,

Background: HIV1 performs highly complex orchestrated tasks during the assembly, budding, maturation and infection stages of the viral replication cycle. During viral assembly, the proteins form membrane associations and self-associations that ultimately result in budding of an immature virion from the infected cell. Gag precursors also function during viral assembly to selectively bind and package two plus strands of genomic RNA. p55 is digested by HIV1 protease into intermediate products p41 and p15. p41 is further digested into matrix protein p17 and capsid protein p24. Likewise, p15 is further digested into nucleocapsid protein p7 and to p6 and p1.