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COPS6 anticorps

COPS6 Reactivité: Humain, Souris, Rat WB, IF (p), IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1385605
  • Antigène Voir toutes COPS6 Anticorps
    COPS6 (COP9 Signalosome Complex Subunit 6 (COPS6))
    Reactivité
    • 35
    • 19
    • 19
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 31
    • 4
    Lapin
    Clonalité
    • 32
    • 3
    Polyclonal
    Conjugué
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp COPS6 est non-conjugé
    Application
    • 25
    • 12
    • 6
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
     Réactivité croisée
    Humain, Souris, Rat
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human COPS6
    Isotype
    IgG
    Top Product
    Discover our top product COPS6 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    COPS6 (COP9 Signalosome Complex Subunit 6 (COPS6))
    Autre désignation
    COPS6 (COPS6 Produits)
    Synonymes
    anticorps CG6932, anticorps CH6, anticorps Csn6, anticorps Dch6, anticorps Dmel\\CG6932, anticorps zgc:112075, anticorps Sgn3, anticorps VIP/MOV34, anticorps CSN6, anticorps MOV34-34KD, anticorps COP9 signalosome subunit 6, anticorps COP-9 SigNalosome subunit, anticorps COPS6, anticorps Cops6, anticorps CSN6, anticorps cops6, anticorps csn-6
    Sujet

    Synonyms: JAB1 containing signalosome subunit 6,COP9 subunit 6 MOV34 homolog, 34 kD,MOV34 homolog, 34 kD,COP9 constitutive photomorphogenic, subunit 6, COP9 complex S6,COP9 signalosome complex subunit 6,COP9 signalosome subunit 6,cops6,CSN6,CSN6_HUMAN,hVIP,JAB1-containing signalosome subunit 6,MOV34 homolog,MOV34-34KD,Sgn3,SGN6,Signalosome subunit 6,VIP/MOV34,Vpr interacting protein,Vpr-interacting protein.

    Background: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. Has some glucocorticoid receptor-responsive activity.

    ID gène
    10980
    Pathways
    Cycle Cellulaire
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