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ANKRD6 anticorps

ANKRD6 Reactivité: Humain, Rat, Souris WB, IF (p), IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1385767
  • Antigène Voir toutes ANKRD6 Anticorps
    ANKRD6 (Ankyrin Repeat Domain 6 (ANKRD6))
    Reactivité
    • 31
    • 16
    • 15
    • 2
    Humain, Rat, Souris
    Hôte
    • 30
    • 1
    Lapin
    Clonalité
    • 30
    • 1
    Polyclonal
    Conjugué
    • 7
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ANKRD6 est non-conjugé
    Application
    • 31
    • 13
    • 13
    • 12
    • 4
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
     Réactivité croisée
    Humain, Souris, Rat
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human ANKRD6/Diversin
    Isotype
    IgG
    Top Product
    Discover our top product ANKRD6 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    ANKRD6 (Ankyrin Repeat Domain 6 (ANKRD6))
    Autre désignation
    ANKRD6 (ANKRD6 Produits)
    Synonymes
    anticorps ANKRD6, anticorps ankrd6, anticorps diversin, anticorps si:dkey-181i3none, anticorps ankyrin repeat domain 6, anticorps ankyrin repeat domain 6b, anticorps ANKRD6, anticorps ankrd6b, anticorps Ankrd6
    Sujet

    Synonyms: ANKRD 6, ankyrin repeat domain 6, ANKR6_HUMAN, Ankyrin repeat domain-containing protein 6, Diversin.

    Background: Diversin, also known as ANKRD6 (ankyrin repeat domain 6), is a 727 amino acid protein that contains eight ankyrin repeats and belongs to the ankyrin repeat domain protein family. Members of the ankyrin repeat domain family facilitate protein-protein interactions and function as adaptors of signaling pathways. Expressed in a developmentally-regulated manner and at highest levels in the brain, Diversin is believed to play a role in brain development. Via its ankyrin repeats, Diversin can directly interact with Dvl (dishevelled), an interaction that is essential for the activation of noncanonical Wnt signaling. In addition, Diversin contains a C-terminal domain that binds Axin/Conductin and a casein kinase-binding domain in its central region that specifically binds casein kinase I?. Through the action of these additional domains, Diversin may also facilitate canonical Wnt signaling. Due to alternative splicing events, three Diversin isoforms exist.

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