LRRC3B anticorps

N° du produit ABIN1385812

Détail du produit anti-LRRC3B anticorps

Antigène: LRRC3B (Leucine Rich Repeat Containing 3B (LRRC3B))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LRRC3B est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human LRP15

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur LRRC3B

Antigène: LRRC3B (Leucine Rich Repeat Containing 3B (LRRC3B))

Autre désignation: LRP15 (LRRC3B Produits)

Synonymes: anticorps LRP15, anticorps BC019794, anticorps RGD1311897, anticorps LRRC3B, anticorps zgc:162270, anticorps leucine rich repeat containing 3B, anticorps LRRC3B, anticorps Lrrc3b, anticorps lrrc3b

Sujet:

Synonyms: LRP 15, LRP-15, Leucine rich repeat containing 3B, Leucine-rich repeat protein LRP15, Leucine-rich repeat-containing protein 3B, LRC3B_HUMAN, LRRC3B, MGC102927.

Background: Leucine-rich repeats (LRRs) are 20-29 amino acid motifs that mediate protein-protein interactions. The primary function of these motifs is to provide a versatile structural framework for the formation of these protein-protein interactions. LRRs are present in a variety of proteins with diverse structure and function, including innate immunity and nervous system development. Several human diseases are associated with mutation in the genes encoding LRR-containing proteins. The leucine-rich repeat-containing protein 3B (LRRC3B), also designated LRP15, is a 259 amino acid protein that contains 3 LRR repeats. The gene encoding LRRC3B is a tumor suppressor gene that is regulated by DNA methylation. Decreased expression of LRRC3B has been shown in colorectal cancer and gastric cancer, making LRRC3B a candidate marker for those cancers.

ID gène: 116135