Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

OTX2 anticorps (AA 15-105)

OTX2 Reactivité: Rat WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1385882
  • Antigène Voir toutes OTX2 Anticorps
    OTX2 (Orthodenticle Homeobox 2 (OTX2))
    Épitope
    • 14
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 15-105
    Reactivité
    • 40
    • 28
    • 15
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Rat
    Hôte
    • 51
    • 4
    Lapin
    Clonalité
    • 50
    • 5
    Polyclonal
    Conjugué
    • 28
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp OTX2 est non-conjugé
    Application
    • 39
    • 19
    • 13
    • 12
    • 12
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
     Réactivité croisée
    Rat
    Homologie
    Human,Mouse,Dog,Cow,Sheep,Horse,Chicken
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human OTX2
    Isotype
    IgG
    Top Product
    Discover our top product OTX2 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    OTX2 (Orthodenticle Homeobox 2 (OTX2))
    Autre désignation
    OTX2 (OTX2 Produits)
    Synonymes
    anticorps CPHD6, anticorps MCOPS5, anticorps E130306E05Rik, anticorps id:ibd2915, anticorps zOtx2, anticorps zgc:136535, anticorps zotx-2, anticorps Xotx-2, anticorps Xotx2, anticorps otx-2, anticorps otx2, anticorps orthodenticle homeobox 2, anticorps orthodenticle homeobox 2 S homeolog, anticorps orthodenticle homeobox 2 L homeolog, anticorps OTX2, anticorps Otx2, anticorps otx2, anticorps otx2.S, anticorps otx2.L
    Sujet

    Synonyms: CPHD6, Homeobox protein OTX2, MCOPS 5, MCOPS5, MGC45000, Orthodenticle 2, Orthodenticle homeobox 2, Orthodenticle homolog 2 Drosophila, Orthodenticle homolog 2, Orthodenticle2, Otx 2, otx2, OTX2_HUMAN.

    Background: Transcription factors, OTX1 and OTX2, are two murine homologs of the Drosophila orthodenticle (OTD), show a limited amino acid sequence divergence. OTX1 and OTX2 play an important role during early and later events required for proper brain development in that they are involved in the processes of induction, specification and regionalization of the brain. OTX1 is involved in corticogenesis, sensory organ development and pituitary functions, while OTX2 is necessary earlier in development, for the correct anterior neural plate specification and organization of the primitive streak. OTX2 is also required in the early specification of the neuroectoderm, which is destined to become the fore-midbrain, and both OTX1 and OTX2 co-operate in patterning the developing brain through a dosage-dependent mechanism. A molecular mechanism depending on a precise threshold of OTX proteins is necessary for the correct positioning of the isthmic region and for anterior brain patterning. The genes which encode OTX1 and OTX2 map to human chromosomes 2p13 and 14q21-q22, respectively.

    Pathways
    Dopaminergic Neurogenesis
Vous êtes ici:
Support technique