ZFYVE27 anticorps (AA 341-411)
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- Antigène Voir toutes ZFYVE27 Anticorps
- ZFYVE27 (Zinc Finger, FYVE Domain Containing 27 (ZFYVE27))
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Épitope
- AA 341-411
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Reactivité
- Humain, Rat, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ZFYVE27 est non-conjugé
- Application
- Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
- Réactivité croisée
- Humain, Souris, Rat
- Homologie
- Dog,Cow,Rabbit
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human ZFYVE27
- Isotype
- IgG
- Top Product
- Discover our top product ZFYVE27 Anticorps primaire
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- Indications d'application
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- ZFYVE27 (Zinc Finger, FYVE Domain Containing 27 (ZFYVE27))
- Autre désignation
- ZFYVE27 (ZFYVE27 Produits)
- Synonymes
- anticorps ZFYVE27, anticorps MGC130947, anticorps spg33, anticorps im:7137347, anticorps zgc:153156, anticorps PROTRUDIN, anticorps RP11-459F3.2, anticorps SPG33, anticorps 2210011N02Rik, anticorps 9530077C24Rik, anticorps AI426636, anticorps AI593546, anticorps AI835681, anticorps zinc finger FYVE-type containing 27, anticorps zinc finger FYVE domain containing 27 L homeolog, anticorps zinc finger FYVE domain containing 27, anticorps zinc finger, FYVE domain containing 27, anticorps ZFYVE27, anticorps zfyve27.L, anticorps zfyve27, anticorps Zfyve27
- Sujet
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Synonyms: Protrudin, RP11 459F3.2, SPG33, ZFY27_HUMAN, ZFYVE27, zinc finger FYVE domain containing 27, Zinc finger FYVE domain containing protein 27, Zinc finger FYVE domain-containing protein 27.
Background: Zinc finger FYVE domain-containing protein 27 (ZFYVE27), also known as SPG33, is a 411 amino acid member of the FYVE-finger family of proteins. The FYVE domain is a cysteine-rich domain of about 70 amino acids that plays a role in the endosomal localization of the FYVE-finger proteins, and a majority of these proteins serve as regulators of endocytic membrane trafficking. ZFYVE27, a multi-pass membrane protein, is an endosomal protein that binds to Spastin, a protein that is primarily involved in microtubule dynamics and severing, vesicular trafficking and endosomal trafficking. Mutations in the gene encoding ZFTVE27 affect neuronal intracellular trafficking in the corticospinal tract and are thought to lead to hereditary spastic paraplegia (HSP), a neurodegenerative disorder, characterized by progressive paralysis of the legs, which is caused by impaired axonal transport. Five isoforms of ZFYVE27 exist as a result of alternative splicing events.
- ID gène
- 118813
- UniProt
- Q5T4F4
- Pathways
- Neurotrophin Signaling Pathway
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