PPFIA1 anticorps (AA 141-190)

N° du produit ABIN1386160

Détail du produit anti-PPFIA1 anticorps

Antigène: PPFIA1 (Protein Tyrosine Phosphatase F Interacting Protein 1 (PPFIA1))

Épitope: AA 141-190

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PPFIA1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Liprin alpha 1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur PPFIA1

Antigène: PPFIA1 (Protein Tyrosine Phosphatase F Interacting Protein 1 (PPFIA1))

Autre désignation: Liprin alpha 1/PPFIA1 (PPFIA1 Produits)

Sujet:

Synonyms: LAR interacting protein 1, LIP 1, LIP.1, LIP1, LIPRIN, MGC26800, PPFIA 1, PPFIA1, Protein tyrosine phosphatase receptor type f polypeptide PTPRF interacting protein liprin alpha 1, Protein tyrosine phosphatase receptor type f polypeptide interacting protein alpha 1, PTPRF interacting protein alpha 1, LIPA1_HUMAN.

Background: Liprins interact with members of the leukocyte common antigen-related (LAR) family of transmembrane protein tyrosine phosphatases, which are implicated in axon guidance and mammary gland development. Liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR phosphatases. Based on sequence similarities and binding characteristics, liprins are subdivided into Alpha and Beta liprins. Both Alpha and Beta liprins homodimerize via their N-terminal, coiled-coil regions. Liprin Alpha1 is a ubiquitously expressed protein that interacts with the tumor suppressor ING4 to regulate cell migration and possibly prevent metastasis. The interaction between LAR and Liprin Alpha1 can be weakened by treatment of Liprin ? with calf intestinal phosphatase.