PPFIA1 anticorps (AA 141-190)
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- Antigène Voir toutes PPFIA1 Anticorps
- PPFIA1 (Protein Tyrosine Phosphatase F Interacting Protein 1 (PPFIA1))
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Épitope
- AA 141-190
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PPFIA1 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Homologie
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human Liprin alpha 1
- Isotype
- IgG
- Top Product
- Discover our top product PPFIA1 Anticorps primaire
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- Indications d'application
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- PPFIA1 (Protein Tyrosine Phosphatase F Interacting Protein 1 (PPFIA1))
- Autre désignation
- Liprin alpha 1/PPFIA1 (PPFIA1 Produits)
- Sujet
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Synonyms: LAR interacting protein 1, LIP 1, LIP.1, LIP1, LIPRIN, MGC26800, PPFIA 1, PPFIA1, Protein tyrosine phosphatase receptor type f polypeptide PTPRF interacting protein liprin alpha 1, Protein tyrosine phosphatase receptor type f polypeptide interacting protein alpha 1, PTPRF interacting protein alpha 1, LIPA1_HUMAN.
Background: Liprins interact with members of the leukocyte common antigen-related (LAR) family of transmembrane protein tyrosine phosphatases, which are implicated in axon guidance and mammary gland development. Liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR phosphatases. Based on sequence similarities and binding characteristics, liprins are subdivided into Alpha and Beta liprins. Both Alpha and Beta liprins homodimerize via their N-terminal, coiled-coil regions. Liprin Alpha1 is a ubiquitously expressed protein that interacts with the tumor suppressor ING4 to regulate cell migration and possibly prevent metastasis. The interaction between LAR and Liprin Alpha1 can be weakened by treatment of Liprin ? with calf intestinal phosphatase.
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