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Neudesin anticorps (AA 51-140)

NENF Reactivité: Humain ELISA, WB, IHC (p), ICC, IF (cc), IF (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1386196
  • Antigène Voir toutes Neudesin (NENF) Anticorps
    Neudesin (NENF)
    Épitope
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 51-140
    Reactivité
    • 14
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 9
    • 3
    • 1
    • 1
    Lapin
    Clonalité
    • 11
    • 3
    Polyclonal
    Conjugué
    • 11
    • 1
    • 1
    • 1
    Cet anticorp Neudesin est non-conjugé
    Application
    • 8
    • 7
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human Neudesin
    Isotype
    IgG
    Top Product
    Discover our top product NENF Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    Neudesin (NENF)
    Autre désignation
    NENF/Neudesin (NENF Produits)
    Synonymes
    anticorps nenf, anticorps CIR2, anticorps SCIRP10, anticorps SPUF, anticorps Spuf, anticorps 1110060M21Rik, anticorps neudesin neurotrophic factor, anticorps neuron derived neurotrophic factor, anticorps nenf, anticorps NENF, anticorps Nenf
    Sujet

    Synonyms: Cell growth inhibiting protein 47, Cell immortalization-related protein 2, CIR2, Nenf, NENF_HUMAN, Neudesin, Neuron derived neurotrophic factor, Neuron-derived neurotrophic factor, SCIRP10, SCIRP10 related protein, Secreted protein of unknown function, Spinal cord injury related protein 10, SPUF, SPUF protein.

    Background: Neudesin is a 172 amino acid secreted protein that belongs to the cytochrome b5 family and MAPR subfamily. Neudesin possesses neurotrophic activity, which is enhanced by binding to heme, and may contribute to neuronal differentiation and neural cell proliferation. In primary cultured neurons, Neudesin has been observed to activate Akt1 and ERK 1 phosphorylation. Upregulated in immortal cells, Neudesin contains one cytochrome b5 heme-binding domain and is encoded by a gene that maps to human chromosome 1q32.3. Human chromosome 1 spans 260 million base pairs and comprises nearly 8 % of the human genome. A large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson?s disease, Gaucher disease, schizophrenia and Usher syndrome, map to chromosome 1.

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