MYLK anticorps (AA 651-750)

N° du produit ABIN1386218

Détail du produit anti-MYLK anticorps

Antigène: MYLK (Myosin Light Chain Kinase (MYLK))

Épitope: AA 651-750

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MYLK est non-conjugé

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Rat

Homologie: Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Chicken,Guinea Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human MLCK

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur MYLK

Antigène: MYLK (Myosin Light Chain Kinase (MYLK))

Autre désignation: MLCK (MYLK Produits)

Synonymes: anticorps AAT7, anticorps KRP, anticorps MLCK, anticorps MLCK1, anticorps MLCK108, anticorps MLCK210, anticorps MSTP083, anticorps MYLK1, anticorps smMLCK, anticorps 9530072E15Rik, anticorps A930019C19Rik, anticorps AW489456, anticorps Mlck, anticorps SMMLCK, anticorps mlck, anticorps fj60a06, anticorps mlck1a, anticorps mylk, anticorps wu:fj60a06, anticorps zmlck1, anticorps myosin light chain kinase, anticorps myosin, light polypeptide kinase, anticorps myosin, light chain kinase a, anticorps MYLK, anticorps Mylk, anticorps mylka

Sujet:

Synonyms: KRP, AAT7, MLCK, MLCK1, MYLK1, s mMLCK, MLCK108, MLCK210, MSTP083, Myosin light chain kinase, smooth muscle, Kinase-related protein, Telokin, MYLK

Background: This gene, a muscle member of the immunoglobulin gene superfamily, encodes myosin light chain kinase which is a calcium/calmodulin dependent enzyme. This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity. This gene encodes both smooth muscle and nonmuscle isoforms. In addition, using a separate promoter in an intron in the 3' region, it encodes telokin, a small protein identical in sequence to the C-terminus of myosin light chain kinase, that is independently expressed in smooth muscle and functions to stabilize unphosphorylated myosin filaments. A pseudogene is located on the p arm of chromosome 3. Four transcript variants that produce four isoforms of the calcium/calmodulin dependent enzyme have been identified as well as two transcripts that produce two isoforms of telokin. Additional variants have been identified but lack full length transcripts. [provided by RefSeq, Jul 2008]

ID gène: 4638

UniProt: Q15746