UFD1L anticorps

N° du produit ABIN1386271

Détail du produit anti-UFD1L anticorps

Antigène: UFD1L (Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UFD1L est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human UFD1L

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur UFD1L

Antigène: UFD1L (Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L))

Autre désignation: UFD1L (UFD1L Produits)

Synonymes: anticorps UFD1, anticorps Ufd1, anticorps ufd1, anticorps wu:fc55f04, anticorps zgc:92341, anticorps Ufd1l, anticorps ubiquitin recognition factor in ER associated degradation 1, anticorps ubiquitin recognition factor in ER-associated degradation 1, anticorps ubiquitin fusion degradation 1 like (yeast), anticorps ubiquitin recognition factor in ER associated degradation 1 S homeolog, anticorps ubiquitin fusion degradation protein 1 homolog, anticorps Ubiquitin Fusion Degradation (yeast UFD homolog), anticorps UFD1, anticorps Ufd1, anticorps UFD1L, anticorps ufd1.S, anticorps ufd1l, anticorps ufd1, anticorps EHI_125920, anticorps LOC100166745, anticorps LOC100635687, anticorps LOC100648660, anticorps ufd-1

Sujet:

Synonyms: UB fusion protein 1, Ubiquitin fusion degradation 1 like yeast, Ubiquitin fusion degradation 1 like, Ubiquitin fusion degradation protein 1 homolog, UFD1, UFD1L.

Background: UFD1L is a member of the UFD1 family of proteins and is a component of the ubiquitin-dependent proteolytic pathway which degrades ubiquitin fusion proteins. This complex, also containing UFD1L, VCP and NPLOC4, binds ubiquitinated proteins and is required for the export of misfolded proteins from the ER to the cytoplasm for disposal. The NPLOC4-UFD1L-VCP complex also regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope. UFD1L gene hemizygosity is the cause of some developmental defects including DiGeorge syndrome (DGS), velo-cardio-facial syndrome (VCFS) and Opitz G/BBB syndrome. UFD1L has 2 named isoforms produced by alternative splicing.

ID gène: 7353