APH1B anticorps (AA 51-150)

N° du produit ABIN1386275

Détail du produit anti-APH1B anticorps

Antigène: APH1B (Aph1b) (Anterior Pharynx Defective 1 Homolog B (Aph1b))

Épitope: AA 51-150

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp APH1B est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Réactivité croisée: Souris

Homologie: Human,Rat,Dog,Cow,Sheep,Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Aph-1b

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur APH1B

Antigène: APH1B (Aph1b) (Anterior Pharynx Defective 1 Homolog B (Aph1b))

Autre désignation: Aph-1b (Aph1b Produits)

Synonymes: anticorps APH-1B, anticorps PRO1328, anticorps PSFL, anticorps TAAV688, anticorps APH-1B', anticorps 2310057K14Rik, anticorps Aph1c, anticorps aph-1 homolog B, gamma-secretase subunit, anticorps aph-1 homolog B, gamma secretase subunit, anticorps aph1 homolog B, gamma secretase subunit, anticorps APH1B, anticorps Aph1b

Sujet:

Synonyms: PSFL, APH-1B, PRO1328, TAAV688, Gamma-secretase subunit APH-1B, Aph-1beta, Presenilin-stabilization factor-like, APH1B, UNQ688/PRO1328

Background: Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex. Probably present in a minority of gamma-secretase complexes compared to APH1A.

ID gène: 83464

UniProt: Q8WW43

Pathways: Signalisation Notch, Neurotrophin Signaling Pathway