PPARG anticorps (AA 315-420)

N° du produit ABIN1386283

Détail du produit anti-PPARG anticorps

Antigène: PPARG (Peroxisome Proliferator-Activated Receptor gamma (PPARG))

Épitope: AA 315-420

Reactivité: Humain, Souris, Rat, Chévre

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PPARG est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Chévre, Humain, Souris, Rat

Homologie: Dog,Cow,Sheep,Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human PPAR Gamma

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-PPARG (ABIN1386283)

Dervishi, Gozutok, Murnan, Gautam, Heller, Bigio, Ozdinler: "Protein-protein interactions reveal key canonical pathways, upstream regulators, interactome domains, and novel targets in ALS." dans: Scientific reports, Vol. 8, Issue 1, pp. 14732, (2019) (PubMed).

Sun, Zeng, Cao, Song, Zhang, Liu: "Vibration Training Triggers Brown Adipocyte Relative Protein Expression in Rat White Adipose Tissue." dans: BioMed research international, Vol. 2015, pp. 919401, (2015) (PubMed).

Détails sur PPARG

Antigène: PPARG (Peroxisome Proliferator-Activated Receptor gamma (PPARG))

Autre désignation: PPAR Gamma (PPARG Produits)

Synonymes: anticorps PPAR gamma, anticorps PPARg2, anticorps PPARG, anticorps Nr1c3, anticorps PPAR-gamma, anticorps PPAR-gamma2, anticorps PPARgamma, anticorps PPARgamma2, anticorps NR1C3, anticorps CIMT1, anticorps GLM1, anticorps PPARG1, anticorps PPARG2, anticorps xPPAR-gamma, anticorps PPAR-GAMMA, anticorps PPARGAMMA, anticorps peroxisome proliferator-activated receptor gamma, anticorps peroxisome proliferator activated receptor gamma, anticorps peroxisome proliferator activated receptor gamma L homeolog, anticorps PPARG, anticorps Pparg, anticorps pparg.L

Sujet:

Synonyms: GLM1, CIMT1, NR1C3, PPARG1, PPARG2, PPARgamma, Peroxisome proliferator-activated receptor gamma, PPAR-gamma, Nuclear receptor subfamily 1 group C member 3, PPARG

Background: Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut homeostasis by suppressing NF-kappa-B-mediated proinflammatory responses. Plays a role in the regulation of cardiovascular circadian rhythms by regulating the transcription of ARNTL/BMAL1 in the blood vessels (By similarity).

ID gène: 5468

UniProt: P37231

Pathways: Signalisation MAPK, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Endopeptidase Activity, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation