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Utrophin anticorps

UTRN Reactivité: Humain, Souris, Rat FACS, ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1386287
  • Antigène Voir toutes Utrophin (UTRN) Anticorps
    Utrophin (UTRN)
    Reactivité
    Humain, Souris, Rat
    Hôte
    • 13
    • 4
    Lapin
    Clonalité
    • 14
    • 3
    Polyclonal
    Conjugué
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Utrophin est non-conjugé
    Application
    • 10
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    Flow Cytometry (FACS), ELISA
     Réactivité croisée
    Humain, Souris, Rat
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human Utrophin
    Isotype
    IgG
    Top Product
    Discover our top product UTRN Anticorps primaire
  • Indications d'application
    IHC-P: 1:100-500, IF(IHC-P): 1:50-200
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C for 12 months.
    Date de péremption
    12 months
  • Antigène
    Utrophin (UTRN)
    Autre désignation
    Utrophin (UTRN Produits)
    Synonymes
    anticorps drp, anticorps dmdl, anticorps drp1, anticorps DKFZp469A0710, anticorps DMDL, anticorps DRP, anticorps DRP1, anticorps AA589569, anticorps Dmdl, anticorps utrophin L homeolog, anticorps utrophin, anticorps utrn.L, anticorps UTRN, anticorps LOAG_03796, anticorps utrn, anticorps LOC100551145, anticorps Utrn
    Sujet

    Synonyms: DMDL, DRP 1, DRP, DRP-1, DRP1, Dystrophin like protein, Dystrophin related protein 1, Dystrophin related protein, Dystrophin-related protein 1, FLJ23678, UTRN, UTRO_HUMAN, Utrophin homologous to dystrophin, Utrophin

    Background: Dystrophin and utrophin are related structural, Actin-binding proteins that are involved in anchoring the cytoskeleton to the plasma membrane. Dystrophin is the protein product of the Duchenne/Becker muscular dystrophy gene. Dystrophin expression is found in muscle and brain tissues, where it is localized to the inner surface of the plasma membrane. It has been speculated that alternative splicing of the carboxy terminus allows dystrophin to interact with a variety of proteins. Research has shown that the loss of dystrophin-associated proteins in Duchenne afflicted muscle is due to the absence of dystrophin rather than to muscle degradation and that the lack of dystrophin results in the loss of linkage between the cytoskeleton and the extracellular matrix. Evidence suggests that the upregulation of utrophin can reduce the dystrophic pathology.

    ID gène
    7402
    Pathways
    Skeletal Muscle Fiber Development
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