FARP2 anticorps (AA 601-700)
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- Antigène Voir toutes FARP2 Anticorps
- FARP2 (FERM, RhoGEF and Pleckstrin Domain Protein 2 (FARP2))
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Épitope
- AA 601-700
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp FARP2 est non-conjugé
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Application
- ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Homologie
- Human,Mouse,Rat,Horse,Chicken
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human FARP2
- Isotype
- IgG
- Top Product
- Discover our top product FARP2 Anticorps primaire
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- Indications d'application
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- FARP2 (FERM, RhoGEF and Pleckstrin Domain Protein 2 (FARP2))
- Autre désignation
- FARP2 (FARP2 Produits)
- Synonymes
- anticorps FARP2, anticorps wu:fc23d05, anticorps wu:fp25d09, anticorps MGC131000, anticorps FIR, anticorps FRG, anticorps PLEKHC3, anticorps AI465173, anticorps BC009153, anticorps D030026M03Rik, anticorps Fir, anticorps mKIAA0793, anticorps FERM, ARH/RhoGEF and pleckstrin domain protein 2, anticorps FERM, RhoGEF and pleckstrin domain protein 2, anticorps FERM, ARH/RhoGEF and pleckstrin domain protein 2 L homeolog, anticorps FARP2, anticorps farp2, anticorps farp2.L, anticorps Farp2
- Sujet
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Synonyms: FARP 2, FERM, FGD1 related Cdc42 GEF, FIR, FRG, KIAA0793, PLEKHC3, RhoGEF and pleckstrin domain protein 2, FARP2_HUMAN.
Background: FARP2 is a 1,545 amino acid protein that contains one FERM domain, one DH domain and two PH domains. It exists as two alternatively spliced isoforms that are abundantly expressed in brain, lung, and testis as well as in embryonic hippocampal and cortical neurons. FARP2 functions as a Rho-guanine nucleotide exchange factor that activates RAC1 and is thought to regulate neurite remodeling of embryonic neurons. Sema3A binding to neuropilin-1 induces the dissociation of FARP2 from plexin-A1, thereby activating FARP2's Rac GEF activity which is critical for repulsion of outgrowing axons and suppression of neuronal adhesion. Downregulation of the FARP2 gene has been implicated in autism.
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