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LAT anticorps (pTyr161)

Name: LAT anticorps (pTyr161)
SKU: ABIN1386362
Price: 384.62 EUR
Availability: InStock

LAT Reactivité: Humain ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated

Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-Phospho-LAT (Tyr161) Polyclonal Antibody, Unconjugated (ABIN1386362) at 1:200 followed by conjugation to the secondary antibody and DAB staining. (LAT anticorps (pTyr161))

IHC

Paraformaldehyde-fixed, paraffin embedded rat spleen tissue, Antigen retrieval by boiling in sodium citrate buffer(pH6) for 15min, Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes, Blocking buffer (normal goat serum) at 37°C for 20min, Antibody incubation with Rabbit Anti-LAT (Tyr161) Polyclonal Antibody, Unconjugated at 1:400 overnight at 4°C, followed by a conjugated secondary and DAB staining (LAT anticorps (pTyr161))

IHC (p)

2 images

N° du produit ABIN1386362

Fiche de données

Antigène Voir toutes LAT Anticorps

LAT (Linker For Activation of T Cells (LAT))
Épitope
20

19

15

8

8

8

7

7

4

4

3

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pTyr161
Reactivité
143

61

43

1
Humain
Hôte
125

19

2

1
Lapin
Anticorps secondaires appropriés
Clonalité
128

19
Polyclonal
Conjugué
70

7

6

6

4

4

4

4

4

3

3

3

3

3

3

3

3

3

3

3

3

2
Cet anticorp LAT est non-conjugé
Application
78

45

38

38

15

13

10

8

6

4

2

2

2

1

1

1
ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie

Human,Mouse,Rat,Cow

Purification

Purified by Protein A.

Immunogène

KLH conjugated synthetic phosphopeptide derived from human LAT around the phosphorylation site of Tyr161

Isotype

IgG

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LAT Reactivité: Humain BCA Hôte: Souris Monoclonal LAT1111 unconjugated

Indications d'application

ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions

For Research Use only
Format

Liquid

Concentration

1 μg/μL

Buffer

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur

ProClin

Précaution d'utilisation

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock

4 °C,-20 °C

Stockage commentaire

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption

12 months
Antigène

LAT (Linker For Activation of T Cells (LAT))

Autre désignation

LAT (LAT Produits)

Synonymes

anticorps LAT, anticorps lat, anticorps LAT1, anticorps pp36, anticorps linker for activation of T-cells, anticorps linker for activation of T cells, anticorps LAT, anticorps lat, anticorps Lat

Sujet

Synonyms: LAT1, pp36, Linker for activation of T-cells family member 1, 36 kDa phospho-tyrosine adapter protein, p36-38, LAT
Background: Required for TCR (T-cell antigen receptor)- and pre-TCR-mediated signaling, both in mature T-cells and during their development. Involved in FCGR3 (low affinity immunoglobulin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, GRB2, GRAP2, and other signaling molecules.

ID gène

27040

UniProt

O43561

Pathways

TCR Signaling, Fc-epsilon Receptor Signaling Pathway