Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

EPH Receptor B1 anticorps (pTyr928)

EPHB1 Reactivité: Souris, Rat WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1386364
  • Antigène Voir toutes EPH Receptor B1 (EPHB1) Anticorps
    EPH Receptor B1 (EPHB1)
    Épitope
    • 21
    • 15
    • 8
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr928
    Reactivité
    • 57
    • 47
    • 41
    • 1
    Souris, Rat
    Hôte
    • 64
    • 4
    • 4
    Lapin
    Clonalité
    • 70
    • 2
    Polyclonal
    Conjugué
    • 31
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp EPH Receptor B1 est non-conjugé
    Application
    • 62
    • 26
    • 26
    • 26
    • 13
    • 11
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
     Réactivité croisée
    Souris, Rat
    Homologie
    Human
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic phosphopeptide derived from human EphB1 around the phosphorylation site of Tyr928
    Isotype
    IgG
    Top Product
    Discover our top product EPHB1 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    EPH Receptor B1 (EPHB1)
    Autre désignation
    Eph receptor B1 (EPHB1 Produits)
    Synonymes
    anticorps ELK, anticorps EPHT2, anticorps Hek6, anticorps NET, anticorps ephb1-a, anticorps xek, anticorps Xek, anticorps MGC89790, anticorps EPHB1, anticorps CEK6, anticorps EK6, anticorps 9330129L11, anticorps AW488255, anticorps C130099E04Rik, anticorps Cek6, anticorps ENSMUSG00000074119, anticorps Elk, anticorps Elkh, anticorps Net, anticorps Ephb2, anticorps Erk, anticorps elk, anticorps EPH receptor B1, anticorps EPH receptor B1 S homeolog, anticorps ephrin type-B receptor 1, anticorps Eph receptor B1, anticorps EPHB1, anticorps ephb1.S, anticorps ephb1, anticorps LOC100467687, anticorps Ephb1
    Sujet

    Synonyms: ELK, NET, Hek6, EPHT2, Ephrin type-B receptor 1, EPH tyrosine kinase 2, EPH-like kinase 6, EK6, Neuronally-expressed EPH-related tyrosine kinase, Tyrosine-protein kinase receptor EPH-2, EPHB1

    Background: Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Cognate/functional ephrin ligands for this receptor include EFNB1, EFNB2 and EFNB3. During nervous system development, regulates retinal axon guidance redirecting ipsilaterally ventrotemporal retinal ganglion cells axons at the optic chiasm midline. This probably requires repulsive interaction with EFNB2. In the adult nervous system together with EFNB3, regulates chemotaxis, proliferation and polarity of the hippocampus neural progenitors. In addition to its role in axon guidance plays also an important redundant role with other ephrin-B receptors in development and maturation of dendritic spines and synapse formation. May also regulate angiogenesis. More generally, may play a role in targeted cell migration and adhesion. Upon activation by EFNB1 and probably other ephrin-B ligands activates the MAPK/ERK and the JNK signaling cascades to regulate cell migration and adhesion respectively.

    ID gène
    2047
    UniProt
    P54762
    Pathways
    Signalisation RTK
Vous êtes ici:
Support technique