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CREB3L3 anticorps (AA 201-300)

CREB3L3 Reactivité: Humain WB, FACS, IF (cc), IF (p), ELISA, IHC (fro), IHC (p), ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1386470
  • Antigène Voir toutes CREB3L3 Anticorps
    CREB3L3 (cAMP Responsive Element Binding Protein 3-Like 3 (CREB3L3))
    Épitope
    • 15
    • 1
    • 1
    • 1
    AA 201-300
    Reactivité
    • 25
    • 8
    • 8
    Humain
    Hôte
    • 25
    Lapin
    Clonalité
    • 25
    Polyclonal
    Conjugué
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CREB3L3 est non-conjugé
    Application
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
     Réactivité croisée
    Humain
    Homologie
    Mouse,Rat,Dog,Cow,Sheep,Pig,Chicken
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human CREB-H
    Isotype
    IgG
    Top Product
    Discover our top product CREB3L3 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    CREB3L3 (cAMP Responsive Element Binding Protein 3-Like 3 (CREB3L3))
    Autre désignation
    CREB-H/CREB3L3 (CREB3L3 Produits)
    Synonymes
    anticorps CREB-H, anticorps CREBH, anticorps BC010786, anticorps D10Bur1e, anticorps creb3l3a, anticorps creb3l3b, anticorps si:dkey-110c1.2, anticorps wu:fc88h05, anticorps zgc:112279, anticorps cAMP responsive element binding protein 3 like 3, anticorps cAMP responsive element binding protein 3-like 3, anticorps cAMP responsive element binding protein 3-like 3a, anticorps CREB3L3, anticorps Creb3l3, anticorps creb3l3a
    Sujet

    Synonyms: cAMP responsive element binding protein 3 like 3, cAMP responsive element-binding protein 3 like protein 3, CREB H, CREB/ATF family transcription factor, CREBH, Cyclic AMP responsive element binding protein 3 like protein 3, cAMP-responsive element-binding protein 3-like protein 3, HYST1481, MGC126553, MGC126557, Transcription factor CREB H, CR3L3_HUMAN.

    Background: CREB3L3 is a 461 amino acid single-pass type II membrane protein that localizes to the endoplasmic reticulum (ER) and, in response to ER stress, is cleaved and translocated to the nucleus. Expressed exclusively in liver, CREB3L3 functions as a transcription factor that, during ER stress, is thought to activate genes that are involved in both the unfolded protein response and the acute phase response (APR). Additionally, CREB3L3 is underexpressed in hepatocellular carcinoma, suggesting a possible role as a tumor suppressor. CREB3L3 functions as a dimer and contains one leucine zipper domain, a KDEL-like sequence and a bZIP domain, through which it conveys its DNA binding ability. Three isoforms of CREB3L3 exist due to alternative splicing events.

    Pathways
    Thyroid Hormone Synthesis
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