CASK anticorps (AA 651-750)

N° du produit ABIN1386520

Détail du produit anti-CASK anticorps

Antigène: CASK (Calcium/calmodulin-Dependent serine Protein Kinase (MAGUK Family) (CASK))

Épitope: AA 651-750

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CASK est non-conjugé

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Réactivité croisée: Rat

Homologie: Human,Mouse,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human CASK

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur CASK

Antigène: CASK (Calcium/calmodulin-Dependent serine Protein Kinase (MAGUK Family) (CASK))

Autre désignation: CASK (CASK Produits)

Synonymes: anticorps CAKI, anticorps CAMGUK, anticorps CG13412, anticorps CG13413, anticorps CG6703, anticorps CMG, anticorps CMG/CASK, anticorps Caki, anticorps CamGUK, anticorps CamguK, anticorps Camguk, anticorps Cask, anticorps Cmg, anticorps DLin-2, anticorps Dmel\\CG6703, anticorps RE09582p, anticorps caki, anticorps camguk, anticorps cmg, anticorps dCASK, anticorps wu:fb70g06, anticorps CAGH39, anticorps FGS4, anticorps LIN2, anticorps MICPCH, anticorps MRXSNA, anticorps TNRC8, anticorps DXPri1, anticorps DXRib1, anticorps LIN-2, anticorps Pals3, anticorps mLin-2, anticorps CG6703 gene product from transcript CG6703-RF, anticorps Peripheral plasma membrane protein CASK, anticorps CAMK/CASK protein kinase, anticorps peripheral plasma membrane protein CASK, anticorps calcium/calmodulin-dependent serine protein kinase b, anticorps calcium/calmodulin-dependent serine protein kinase a, anticorps calcium/calmodulin dependent serine protein kinase, anticorps calcium/calmodulin-dependent serine protein kinase (MAGUK family), anticorps calcium/calmodulin-dependent serine protein kinase (MAGUK family) S homeolog, anticorps CASK, anticorps Bm1_33725, anticorps LOAG_17286, anticorps Tsp_03763, anticorps caskb, anticorps caska, anticorps Cask, anticorps cask.S

Sujet:

Synonyms: CAGH39, Caki, Calcium/calmodulin dependent serine protein kinase, Calcium/calmodulin dependent serine protein kinase MAGUK family, Calcium/calmodulin dependent serine protein kinase membrane associated guanylate kinase, Calcium/calmodulin-dependent serine protein kinase, CAMGUK, CAMGUK protein, CAMGUK, drosophila, homolog of antibody casK, CMG, CSKP_HUMAN, DXPri1, DXRib1, FGS4, hCASK, LIN 2, Lin 2 homolog, LIN2 antibody Lin2 homolog, MICPCH, MRXSNA, Pals3, Peripheral plasma membrane protein CASK, Protein lin-2 homolog, TNRC8, Trinucleotide repeat containing 8, Vertebtate LIN2 homolog.

Background: The MAGUK (membrane-associated guanylate kinase homologs) family of proteins contain multiple protein-binding domains and are involved in cell junction organization, tumor suppression, and signaling. CASK (also designated LIN-2) belongs to a MAGUK subfamily which is characterized by a novel domain structure that consists of a calcium/calmodulin- dependent protein kinase domain followed by PDZ, SH3 and guanylate kinase-like (GUK) domains. CASK is expressed in rat brain where it binds to cell-surface proteins, such as neurexin and syndecan, and is thought to be involved in signaling at neuronal synapses. CASK translocates to the nucleus and interacts with Tbr-1 to form a complex, which binds to a specific DNA sequence (the T-element), and induces the expression of specific genes, including Reelin. CASK displays a transcription regulation function, which appears crucial for cerebrocortical development.

Pathways: Synaptic Vesicle Exocytosis