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NPDC1 anticorps (AA 75-180)

NPDC1 Reactivité: Souris WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro), ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1386609
  • Antigène Voir toutes NPDC1 Anticorps
    NPDC1 (Neural Proliferation, Differentiation and Control, 1 (NPDC1))
    Épitope
    • 14
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    AA 75-180
    Reactivité
    • 28
    • 25
    • 7
    • 1
    • 1
    • 1
    • 1
    Souris
    Hôte
    • 36
    • 2
    • 1
    Lapin
    Clonalité
    • 37
    • 2
    Polyclonal
    Conjugué
    • 17
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp NPDC1 est non-conjugé
    Application
    • 28
    • 12
    • 12
    • 10
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
     Réactivité croisée
    Souris
    Homologie
    Human,Rat
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human NPDC1
    Isotype
    IgG
    Top Product
    Discover our top product NPDC1 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    NPDC1 (Neural Proliferation, Differentiation and Control, 1 (NPDC1))
    Autre désignation
    NPDC1 (NPDC1 Produits)
    Synonymes
    anticorps AI314472, anticorps NPDC-1, anticorps CAB, anticorps CAB-, anticorps CAB-1, anticorps CAB1, anticorps neural proliferation, differentiation and control, 1, gene 1 L homeolog, anticorps neural proliferation, differentiation and control 1, anticorps neural proliferation, differentiation and control, 1, anticorps npdc1.1.L, anticorps Npdc1, anticorps NPDC1
    Sujet

    Synonyms: AI314472, CAB1, Neural proliferation dferentiation and control protein 1, NPDC-1, NPDC1, NPDC1_HUMAN.

    Background: NPDC-1 (Neural Proliferation Differentiation and Control-1) is expressed in neurons once they have stopped dividing and begun to differentiate. NPDC-1 is transported from the Golgi apparatus via vesicles before becoming internalized by endosomes at the cell membrane. NPDC-1 interacts with Cdk2, D-type cyclins, and the transcription factor E2F1. This interaction can lead to an increased replication time, and might have implications in final neural differentiation and apoptosis. NPDC-1 has been shown to colocalize with synaptic vesicle proteins: synaptophysin, synaptobrevin 2, and Rab3 GEP (Rab3 GTP/GDP exchange protein). One function of NPDC-1 is to regulate retinoic acid-mediated events by directly interacting with retinoid receptors. The amino acid sequence of NPDC-1 is highly conserved between mouse, rat, and human.

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