P2RY14 anticorps (AA 125-230)
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- Antigène Voir toutes P2RY14 Anticorps
- P2RY14 (Purinergic Receptor P2Y, G-Protein Coupled, 14 (P2RY14))
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Épitope
- AA 125-230
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp P2RY14 est non-conjugé
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Application
- ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Homologie
- Human,Mouse,Rat
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human G-protein coupled receptor 105
- Isotype
- IgG
- Top Product
- Discover our top product P2RY14 Anticorps primaire
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- Indications d'application
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- P2RY14 (Purinergic Receptor P2Y, G-Protein Coupled, 14 (P2RY14))
- Autre désignation
- GPR105 (P2RY14 Produits)
- Synonymes
- anticorps BPR105, anticorps GPR105, anticorps P2Y14, anticorps A330108O13Rik, anticorps Gpr105, anticorps purinergic receptor P2Y, G-protein coupled, 14, anticorps purinergic receptor P2Y14, anticorps P2RY14, anticorps P2ry14
- Sujet
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Synonyms: A330108O13Rik, G protein coupled receptor for UDP-glucose, G protein-coupled receptor 105, G protein-coupled receptor VTR 15-20, G-protein coupled receptor 105, GPR105, KIAA0001, P2RY14, P2Y purinoceptor 14, P2Y14 receptor, P2Y14, P2Y14 receptor, P2Y14_HUMAN, Purinergic receptor P2Y G protein coupled 14, Similar to TYPE-1 Angiotensin II receptor, UDP-glucose receptor, GPCR GPR105.
Background: G protein-coupled receptors (GPRs) are a protein family of transmembrane receptors that transmit an extracellular signal (ligand binding) into an intracellular signal (G protein activation). GPR signaling is an evolutionarily ancient mechanism used by all eukaryotes to sense environmental stimuli and mediate cell-cell communication. All of the receptors have seven membrane-spanning domains and the extracellular parts of the receptor can be glycosylated. These extracellular loops also contain two highly conserved cysteine residues which create disulfide bonds to stabilize the receptor structure. GPR105, also designated P2Y14, is widely expressed throughout many brain regions where it localizes to glial cells, and specifically co-localizes with astrocytes. GPR105 is upregulated when a tissue is immunologically challenged with lipopolysaccharide, leading to the theory that GPR105 may play an important role in modulating peripheral and neuroimmune function.
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