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DLGAP2 anticorps (AA 251-360)

DLGAP2 Reactivité: Humain, Rat WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1386703
  • Antigène Voir toutes DLGAP2 Anticorps
    DLGAP2 (Discs, Large (Drosophila) Homolog-Associated Protein 2 (DLGAP2))
    Épitope
    • 14
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 251-360
    Reactivité
    • 21
    • 16
    • 4
    Humain, Rat
    Hôte
    • 23
    Lapin
    Clonalité
    • 23
    Polyclonal
    Conjugué
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp DLGAP2 est non-conjugé
    Application
    • 19
    • 12
    • 12
    • 6
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
     Réactivité croisée
    Humain, Rat
    Homologie
    Mouse
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human SAPAP2/DLGAP2
    Isotype
    IgG
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    DLGAP2 (Discs, Large (Drosophila) Homolog-Associated Protein 2 (DLGAP2))
    Autre désignation
    SAPAP2/DLGAP2 (DLGAP2 Produits)
    Synonymes
    anticorps PSD-95, anticorps DAP2, anticorps SAPAP2, anticorps 6430596N04Rik, anticorps Sapap2, anticorps DLG associated protein 2, anticorps disks large-associated protein 2, anticorps discs, large (Drosophila) homolog-associated protein 2a, anticorps discs, large (Drosophila) homolog-associated protein 2, anticorps DLGAP2, anticorps LOC463960, anticorps dlgap2a, anticorps LOC100447448, anticorps Dlgap2
    Sujet

    Synonyms: DAP-2, DAP2, Discs large Drosophila homolog associated protein 2, Discs large homolog associated protein 2, Disks large-associated protein 2, Dlgap2, DLGP2_HUMAN, PSD-95/SAP90-binding protein 2, SAP90/PSD-95-associated protein 2, SAPAP2, hide.

    Background: A guanylate kinase is a phosphotransferase that produces ADP and GDP from the substrates ATP and GMP. SAPAP2, also known as DAP-2 (Disks large-associated protein 2) and PSD-95/SAP90-binding protein 2, is a 1054 amino acid protein that localizes to the postsynaptic membrane of neuronal cells of the brain and kidney. SAPAP2 likely acts as a signaling molecule which interacts with the human genes DLG1 and DLG4/PSD-95. The gene encoding SAPAP2, DLGAP2, maps to human chromosome 8. Consisting of nearly 146 million base pairs, chromosome 8 encodes over 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that maps to chromosome 8.

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