SLC51B anticorps (AA 1-35)

N° du produit ABIN1386750

Détail du produit anti-SLC51B anticorps

Antigène: SLC51B (OSTBETA) (Organic Solute Transporter beta (OSTBETA))

Épitope: AA 1-35

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLC51B est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Souris

Homologie: Human,Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human OST-beta

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-SLC51B (ABIN1386750)

Stipanuk, Jurkowska, Niewiadomski, Mazor, Roman, Hirschberger: "Identification of Taurine-Responsive Genes in Murine Liver Using the Cdo1-Null Mouse Model." dans: Advances in experimental medicine and biology, Vol. 975, pp. 475-495, (2017) (PubMed).

Détails sur SLC51B

Antigène: SLC51B (OSTBETA) (Organic Solute Transporter beta (OSTBETA))

Autre désignation: OST-beta (OSTBETA Produits)

Synonymes: anticorps Ostb, anticorps Ostbeta, anticorps RGD1565748, anticorps OSTB, anticorps OSTBETA, anticorps solute carrier family 51, beta subunit, anticorps solute carrier family 51 beta subunit, anticorps Slc51b, anticorps SLC51B

Sujet:

Synonyms: organic solute transporter beta Ostbeta, Organic solute transporter subunit beta, Ostbeta, Ost beta, OST-beta, OSTB, OSTB_HUMAN.

Background: The heteromeric transporter OST Alpha/OST Beta facilitates the transport of bile and other steroid solutes across the basolateral epithelial cell membrane of intestine, liver, testis, kidney and adrenal gland. OST Alpha/OST Beta expression is induced by bile acids through ligand-dependent transactivation of their genes by FXR (Farnesoid X-activated receptor). This genetic regulation suggests that in response to changes in intracellular bile acid levels, bile acids adjust the rate of their own efflux from enterocytes. OST Beta is a 128 amino acid single-pass transmembrane protein that requires OST Alpha to localize to the plasma membrane. Coexpression of OST Alpha and OST Beta is also required to convert the OST Alpha subunit to a mature glycosylated endoglycosidase H-resistant form, suggesting that co-expression facilitates trafficking of OST Alpha through the golgi apparatus. Though widely expressed, OST Beta is present at highest levels in ileum.

ID gène: 123264

Pathways: Regulation of Carbohydrate Metabolic Process