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DIRC2 anticorps (AA 51-150)

DIRC2 Reactivité: Humain, Rat WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1386794
  • Antigène Voir toutes DIRC2 Anticorps
    DIRC2 (Disrupted in Renal Carcinoma 2 (DIRC2))
    Épitope
    • 14
    • 7
    • 1
    • 1
    • 1
    • 1
    AA 51-150
    Reactivité
    • 32
    • 15
    • 10
    • 2
    • 2
    • 2
    • 1
    Humain, Rat
    Hôte
    • 32
    Lapin
    Clonalité
    • 32
    Polyclonal
    Conjugué
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp DIRC2 est non-conjugé
    Application
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
     Réactivité croisée
    Humain, Rat
    Homologie
    Mouse,Dog,Sheep,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human DIRC2
    Isotype
    IgG
    Top Product
    Discover our top product DIRC2 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    DIRC2 (Disrupted in Renal Carcinoma 2 (DIRC2))
    Autre désignation
    Dirc2 (DIRC2 Produits)
    Synonymes
    anticorps MGC80843, anticorps zgc:92095, anticorps rcc4, anticorps MGC69320, anticorps RCC4, anticorps disrupted in renal carcinoma 2, anticorps disrupted in renal carcinoma 2 L homeolog, anticorps disrupted in renal carcinoma 2 (human), anticorps DIRC2, anticorps dirc2.L, anticorps dirc2, anticorps Dirc2
    Sujet

    Synonyms: Disrupted in renal carcinoma protein 2, DIRC 2, Disrupted in renal cancer protein 2, Disrupted in renal carcinoma 2, FLJ14784, NP_116228, RCC 4, RCC4, Renal cell carcinoma 4, DIRC2_HUMAN.

    Background: Belonging to the major facilitator superfamily, DIRC2 (disrupted in renal carcinoma protein 2) is a 478 amino acid multi-pass membrane protein that is primarily expressed in kidney proximal tubular cells. The genes encoding DIRC2 and DIRC3 are located at a translocation breakpoint which occurs frequently in individuals affected by familial renal cell carcinoma. Fusion transcripts that result from these translocations may affect normal protein function. This evidence suggests that, due to its chromosomal location, deregulation of the DIRC2 gene may cause haploinsufficiency and therefore result in the onset of tumor growth. There are two isoforms of DIRC2 which are produced as a result of alternative splicing events.

    ID gène
    84925
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