PANK1 anticorps

N° du produit ABIN1386809

Détail du produit anti-PANK1 anticorps

Antigène: PANK1 (Pantothenate Kinase 1 (PANK1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PANK1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human PANK1

Isotype: IgG

Information d'application

Indications d'application: WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur PANK1

Antigène: PANK1 (Pantothenate Kinase 1 (PANK1))

Autre désignation: PANK1 (PANK1 Produits)

Synonymes: anticorps PANK, anticorps 4632412I06Rik, anticorps 5430426F23Rik, anticorps Pank, anticorps Pank1a, anticorps Pank1b, anticorps panK1beta, anticorps PANK1, anticorps im:7149302, anticorps wu:fb51a11, anticorps zgc:158746, anticorps ATCOAA, anticorps ATPANK1, anticorps T13D8.31, anticorps T13D8_31, anticorps pantothenate kinase 1, anticorps DKFZp469J1021, anticorps fb79e08, anticorps zgc:63556, anticorps wu:fb79e08, anticorps pantothenate kinase 1, anticorps pantothenate kinase 1b, anticorps pantothenate kinase 1a, anticorps PANK1, anticorps Pank1, anticorps pank1b, anticorps EHI_183060, anticorps pank1a

Sujet:

Synonyms: coaA, hPanK, hPanK1, PANK, PANK1, PANK1_HUMAN, PANK1a, PANK1b, PanK1beta, Pantothenate kinase 1, Pantothenate kinase, Pantothenic acid kinase 1.

Background: The pantothenate kinase (PANK) family of proteins catalyzes the first step in coenzyme A (CoA). Pantothenate kinase 1 (PANK1) is a 598 amino acid member of the pantothenate kinase family that plays a role in the physiological regulation of the intracellular CoA concentration. Localized to the cytoplasm, PANK1 is strongly inhibited by acetyl-CoA and manyl-CoA, as well as by high concentration of non-esterified CoA (CoASH). Four known isoforms of PANK1 exist as a result of alternative splicing events. Of these isoforms, PANK1a and PANK1b have been identified as the catalytically active isoforms. Isoform PANK1a is most highly expressed in brain, heart, kidney, liver, skeletal muscle and kidney. Isoform PANK1b is detected at much lower levels in kidney, liver, brain and testis and is not detected in heart or skeletal muscle.

ID gène: 53354

UniProt: Q8TE04

Pathways: Ribonucleoside Biosynthetic Process