SKP1 anticorps (AA 81-163)

N° du produit ABIN1386819

Détail du produit anti-SKP1 anticorps

Antigène: SKP1 (S-Phase Kinase-Associated Protein 1 (SKP1))

Épitope: AA 81-163

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SKP1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Souris, Rat

Homologie: Human,Sheep

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human SKP1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur SKP1

Antigène: SKP1 (S-Phase Kinase-Associated Protein 1 (SKP1))

Autre désignation: SKP1 (SKP1 Produits)

Synonymes: anticorps EMC19, anticorps OCP-II, anticorps OCP2, anticorps SKP1A, anticorps TCEB1L, anticorps p19A, anticorps 15kDa, anticorps 2610043E24Rik, anticorps 2610206H23Rik, anticorps SKP1, anticorps Tceb1l, anticorps p19Skp1, anticorps Skp1a, anticorps skp1a, anticorps zgc:73186, anticorps ocp2, anticorps emc19, anticorps ocp-ii, anticorps tceb1l, anticorps ARABIDOPSIS SKP1 HOMOLOGUE 1, anticorps ASK1, anticorps ATSKP1, anticorps S phase kinase-associated protein 1, anticorps T4O12.17, anticorps T4O12_17, anticorps UFO INTERACTING PROTEIN 1, anticorps UIP1, anticorps ocp-2, anticorps S-phase kinase associated protein 1, anticorps S-phase kinase-associated protein 1, anticorps S-phase kinase-associated protein 1 pseudogene, anticorps S-phase kinase-associated protein 1A, anticorps S-phase kinase-associated protein 1 S homeolog, anticorps S phase kinase-associated protein 1, anticorps SKP1, anticorps skp1, anticorps LOC100340043, anticorps Skp1a, anticorps Skp1, anticorps skp1.S

Sujet:

Synonyms: Cyclin A/CDK2 associated p19, Cyclin A/CDK2 associated protein p19, Cyclin-A/CDK2-associated protein p19, EMC 19, EMC19, OCP 2, OCP II, OCP II protein, OCP-2, OCP-II, OCP2, OCPII, organ of Corti protein 2, Organ of Corti protein II, p19A, p19skp1, RNA polymerase II elongation factor like protein, RNA polymerase II elongation factor like protein OCP2, RNA polymerase II elongation factor-like protein, S phase kinase associated protein 1, S phase kinase associated protein 1A, S phase kinase associated protein 1A p19A, S-phase kinase-associated protein 1, SIII, Skp 1, SKP 1A, skp1, SKP1_HUMAN, SKP1A, TCEB1L, Transcription elongation factor B SIII polypeptide 1 like, Transcription Elongation Factor B 1 like, Transcription Elongation Factor B 1-like, Transcription elongation factor B, Transcription elongation factor B SIII polypeptide 1 like.

Background: Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1. SCF(BTRC) mediates the ubiquitination of NFKBIA at 'Lys-21' and 'Lys-22', the degradation frees the associated NFKB1-RELA dimer to translocate into the nucleus and to activate transcription. SCF(Cyclin F) directs ubiquitination of CP110.

ID gène: 6500

Pathways: Cycle Cellulaire, Signalisation Hedgehog, Mitotic G1-G1/S Phases