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FBXO11 anticorps (AA 65-160)

FBXO11 Reactivité: Humain ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1386847
  • Antigène Voir toutes FBXO11 Anticorps
    FBXO11 (F-Box Protein 11 (FBXO11))
    Épitope
    • 14
    • 7
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 65-160
    Reactivité
    • 62
    • 19
    • 16
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 56
    • 5
    • 1
    Lapin
    Clonalité
    • 59
    • 3
    Polyclonal
    Conjugué
    • 27
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp FBXO11 est non-conjugé
    Application
    • 34
    • 24
    • 12
    • 12
    • 6
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Homologie
    Human,Mouse,Rat,Cow,Sheep,Pig,Horse,Chicken
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human FBXO11
    Isotype
    IgG
    Top Product
    Discover our top product FBXO11 Anticorps primaire
  • Indications d'application
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    FBXO11 (F-Box Protein 11 (FBXO11))
    Autre désignation
    FBXO11 (FBXO11 Produits)
    Synonymes
    anticorps FBX11, anticorps PRMT9, anticorps UBR6, anticorps VIT1, anticorps C80048, anticorps Jf, anticorps Vit1, anticorps fbxo11, anticorps MGC84634, anticorps FBXO11, anticorps im:6906507, anticorps wu:fj83f06, anticorps zgc:153171, anticorps Fbxo11, anticorps DKFZp459P2410, anticorps F-box protein 11, anticorps F-box protein 11 L homeolog, anticorps F-box protein 11a, anticorps F-box only protein 11, anticorps hypothetical protein, anticorps FBXO11, anticorps Fbxo11, anticorps fbxo11.L, anticorps fbxo11a, anticorps CpipJ_CPIJ009919, anticorps CpipJ_CPIJ017549, anticorps Bm1_52225, anticorps LOAG_16571, anticorps fbxo11, anticorps LOC100115478
    Sujet

    Synonyms: UBR6, VIT1, FBX11, PRMT9, UG063H01, F-box only protein 11, Protein arginine N-methyltransferase 9, Vitiligo-associated protein 1, VIT-1, FBXO11

    Background: Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins, such as DTL/CDT2, BCL6 and PRDM1/BLIMP1. The SCF(FBXO11) complex mediates ubiquitination and degradation of BCL6, thereby playing a role in the germinal center B-cells terminal differentiation toward memory B-cells and plasma cells. The SCF(FBXO11) complex also mediates ubiquitination and degradation of DTL, an important step for the regulation of TGF-beta signaling, cell migration and the timing of the cell-cycle progression and exit. Binds to and neddylates phosphorylated p53/TP53, inhibiting its transcriptional activity. SCF(FBXO11) does not seem to direct ubiquitination of p53/TP53.

    ID gène
    80204
    UniProt
    Q86XK2
    Pathways
    Sensory Perception of Sound
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