FBXL21 anticorps (AA 121-220)

N° du produit ABIN1386850

Détail du produit anti-FBXL21 anticorps

Antigène: FBXL21 (F-Box and Leucine-Rich Repeat Protein 21 (FBXL21))

Épitope: AA 121-220

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FBXL21 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Souris

Homologie: Human,Rat,Dog,Cow,Sheep

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human FBXL21/FBL3B

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur FBXL21

Antigène: FBXL21 (F-Box and Leucine-Rich Repeat Protein 21 (FBXL21))

Autre désignation: FBXL21 (FBXL21 Produits)

Synonymes: anticorps D630045D17Rik, anticorps FBL3B, anticorps FBXL3B, anticorps Psttm, anticorps FBXL3P, anticorps Fbl21, anticorps F-box and leucine rich repeat protein 21, anticorps F-box and leucine-rich repeat protein 21, anticorps F-box and leucine rich repeat protein 21 (gene/pseudogene), anticorps FBXL21, anticorps Fbxl21

Sujet:

Synonyms: F box and leucine rich repeat protein 21, F box and leucine rich repeat protein 3 pseudogene, F box and leucine rich repeat protein 3B, F box protein Fbl3b, F box/LRR repeat protein 21, F box/LRR repeat protein 3B, Fbl 21, FBXL 21, FBXL-21, FBL 3, FBL 3B, Fbl21, FBL3, FBL-3B, FBL 3B, FBL3B, FBXL 21, FBXL 3B, FBXL 3P, FBXL3B, FBXL3P, MGC120237, FXL21_HUMAN.

Background: FBL3B is a 434 amino acid protein encoded by the human gene FBXL21. FBL3B contains one 40 amino acid F-box region, making it a member of the F-box family. FBL3B also contains three LRR (leucine-rich) repeats. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. F-box proteins are members of a large family that regulates cell cycle, immune response, signaling cascades and developmental programs by targeting proteins, such as cyclins, cyclin-dependent kinase inhibitors, IkB-a and b-catenin, for degradation by the proteasome after ubiquitination. FBL3B is a substrate-recognition component of the SCF complex that interacts with Skp1 p19 and CUL-1. FBL3B is also associated with expression and regulation of circadian and cryptochrome proteins.

ID gène: 26223

Pathways: Photoperiodism