FBXO7 anticorps (AA 251-350)

N° du produit ABIN1386851

Détail du produit anti-FBXO7 anticorps

Antigène: FBXO7 (F-Box Protein 7 (FBXO7))

Épitope: AA 251-350

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FBXO7 est non-conjugé

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human FBXO7

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur FBXO7

Antigène: FBXO7 (F-Box Protein 7 (FBXO7))

Autre désignation: FBXO7 (FBXO7 Produits)

Synonymes: anticorps fbxo7, anticorps MGC80085, anticorps FBXO7, anticorps fbx7, anticorps MGC135804, anticorps MGC145325, anticorps ATFBP7, anticorps F-BOX PROTEIN 7, anticorps F-box protein 7, anticorps F8K7.20, anticorps F8K7_20, anticorps DKFZp469H0739, anticorps si:ch211-286m4.2, anticorps zgc:114096, anticorps FBX, anticorps FBX07, anticorps FBX7, anticorps PARK15, anticorps PKPS, anticorps 2410015K21Rik, anticorps A230052G17Rik, anticorps AI117679, anticorps AW260462, anticorps C85118, anticorps F-box protein 7, anticorps F-box protein 7 L homeolog, anticorps FBXO7, anticorps fbxo7.L, anticorps fbxo7, anticorps FBP7, anticorps Fbxo7

Sujet:

Synonyms: F box only protein 7, F box protein 7, F-box protein 7, FBX, FBX07, FBX7, PARK15, PKPS,

Background: FBXO7, also known as FBX, FBX7 or PKPS, is a 522 amino acid protein that contains one F-box domain and functions as a component of the SCF complex. Defects in the gene encoding FBXO7 are associated with parkinsonian-pyramidal syndrome (PKPS), a hypokinetic rigid disorder that exhibits Parkinsonian and pyramidal-associated symptoms.The FBXO7 gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it may play a role in regulation of hematopoiesis. Alternatively spliced transcript variants of this gene have been identified with the full-length natures of only some variants being determined.

ID gène: 25793