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OLIG1 anticorps (AA 121-220)

OLIG1 Reactivité: Rat WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1386861
  • Antigène Voir toutes OLIG1 Anticorps
    OLIG1 (Oligodendrocyte Transcription Factor 1 (OLIG1))
    Épitope
    • 14
    • 8
    • 8
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 121-220
    Reactivité
    • 33
    • 32
    • 25
    • 7
    • 6
    • 5
    • 3
    • 3
    • 3
    • 1
    Rat
    Hôte
    • 61
    • 3
    Lapin
    Clonalité
    • 60
    • 4
    Polyclonal
    Conjugué
    • 32
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp OLIG1 est non-conjugé
    Application
    • 59
    • 28
    • 12
    • 12
    • 6
    • 6
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
     Réactivité croisée
    Rat
    Homologie
    Human,Mouse,Dog,Cow,Pig
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human OLIG1
    Isotype
    IgG
    Top Product
    Discover our top product OLIG1 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    OLIG1 (Oligodendrocyte Transcription Factor 1 (OLIG1))
    Autre désignation
    OLIG1 (OLIG1 Produits)
    Synonymes
    anticorps OLIG1, anticorps BHLHB6, anticorps BHLHE21, anticorps AI836478, anticorps AW494459, anticorps Bhlhb6, anticorps Olg-1, anticorps Oligo1, anticorps bHLHe21, anticorps Olg1, anticorps oligodendrocyte transcription factor 1, anticorps OLIG1, anticorps Olig1
    Sujet

    Synonyms: Oligo 1, Oligo1, Oligodendrocyte lineage transcription factor 1, Oligodendrocyte specic bHLH transcription factor 1, Oligodendrocyte transcription factor 1. Basic domain helix loop helix protein class B 6, Basic domain helix loop helix protein class B6, BHLH B6, BHLHB 6, BHLHB6, bHLHe21, Class B basic helix-loop-helix protein 6, Class E basic helix-loop-helix protein 21, Olig 1, Olig1, OLIG1_HUMAN.

    Background: The oligodendrocyte lineage-specific basic helix-loop-helix (OLIG) family of transcription factors include OLIG1-OLIG3, which differ in tissue expression. OLIG1 and OLIG2 are specifically expressed in nervous tissue as gene regulators of oligodendrogenesis. OLIG2 is more widely expressed in embryonic brain than OLIG1, while OLIG3 is primarily expressed in non-neural tissues. OLIG1 and OLIG2 interact with the Nkx-2.2 homeodomain protein, which is responsible for directing ventral neuronal patterning in response to graded Sonic hedgehog signaling in the embryonic neural tube. These interactions between OLIG proteins and Nkx-2.2 appear to promote the formation of alternate cell types by inhibiting V3 interneuron development. OLIG1 and OLIG2 are abundantly expressed in oligodendroglioma and nearly absent in astrocytomas. Therefore, OLIG proteins are candidates for molecular markers of human glial brain tumors, which are the most common primary malignancies of the human brain.

    ID gène
    116448
    UniProt
    Q8TAK6
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