UGCG anticorps (AA 31-98)

N° du produit ABIN1386872

Détail du produit anti-UGCG anticorps

Antigène: UGCG (UDP-Glucose Ceramide Glucosyltransferase (UGCG))

Épitope: AA 31-98

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UGCG est non-conjugé

Application: Western Blotting (WB), ELISA

Réactivité croisée: Souris, Rat

Homologie: Human,Dog,Cow,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human UGCG

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur UGCG

Antigène: UGCG (UDP-Glucose Ceramide Glucosyltransferase (UGCG))

Autre désignation: UGCG (UGCG Produits)

Synonymes: anticorps GCS, anticorps GLCT1, anticorps XLCGT, anticorps gcs, anticorps glct1, anticorps ugcga, anticorps xlcgt, anticorps cb539, anticorps sb:cb539, anticorps zgc:112506, anticorps ugcg, anticorps ugcgb, anticorps AU043821, anticorps C80537, anticorps Epcs21, anticorps GlcT-1, anticorps Ugcgl, anticorps UDP-glucose ceramide glucosyltransferase, anticorps UDP-glucose ceramide glucosyltransferase L homeolog, anticorps UDP-glucose ceramide glucosyltransferase S homeolog, anticorps UGCG, anticorps ugcg.L, anticorps Ugcg, anticorps ugcg, anticorps ugcg.S

Sujet:

Synonyms: CEGT_HUMAN, Ceramide glucosyltransferase, GCS, GLCT 1, GLCT-1, GLCT1, Glucosylceramide synthase, UDP glucose ceramide glucosyltransferase, UDP glucose N acylsphingosine D glucosyltransferase, UDP-glucose ceramide glucosyltransferase, UDP-glucose:N-acylsphingosine D-glucosyltransferase, Ugcg.

Background: Glucosylceramide synthase (GCS), also designated ceramide glucosyltransferase, belongs to the glycosyltransferase 2 family. It is a widely expressed integral membrane protein encoded by UGCG. The enzyme can be found in the plasma membrane of all eukaryotic cells, and a significant concentration of glucosylceramide synthase activity has been reported in the Golgi complex. Glucosylceramide synthase catalyzes the first glycosylation step in glycosphingolipid biosynthesis and functions as a glucosyltransferase and flippase in the transfer of glucose to ceramide. Glucosylceramide synthase operates in cell recognition, cell proliferation and differentiation, immune recognition and signal transduction. The regulation of ceramide levels through glucosylceramide synthase has been associated with the induction of apoptosis and notable research implicates this relationship with drug-induced apoptosis in a variety of cell types.