CDC14A anticorps (AA 51-150)

N° du produit ABIN1386873

Détail du produit anti-CDC14A anticorps

Antigène: CDC14A (CDC14 Cell Division Cycle 14 Homolog A (CDC14A))

Épitope: AA 51-150

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDC14A est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain, Souris

Homologie: Rat,Dog,Cow,Sheep,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Cdc14A

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur CDC14A

Antigène: CDC14A (CDC14 Cell Division Cycle 14 Homolog A (CDC14A))

Autre désignation: Cdc14A (CDC14A Produits)

Synonymes: anticorps cdc14, anticorps hCDC14, anticorps xcdc14a, anticorps A830059A17Rik, anticorps CDC14A2, anticorps CDC14a1, anticorps Cdc14, anticorps CDC14A, anticorps zgc:63654, anticorps cell division cycle 14A, anticorps Dual specificity protein phosphatase CDC14A, anticorps dual specificity protein phosphatase CDC14A, anticorps cell division cycle 14A L homeolog, anticorps CDC14 cell division cycle 14A, anticorps cell division cycle 14Aa, anticorps CDC14A, anticorps TVAG_168700, anticorps TVAG_479730, anticorps TVAG_362610, anticorps TVAG_490830, anticorps GL50803_9270, anticorps CMU_014610, anticorps cdc14a.L, anticorps Cdc14a, anticorps cdc14a, anticorps cdc14aa

Sujet:

Synonyms: CDC 10, Cdc 14, Cdc 14A, Cdc 14A1, Cdc 14A2, CDC10, Cdc14, CDC14 cell division cycle 14 homolog A, CDC14 homolog A, Cdc14A1, Cdc14A2, Cell division cycle 14 homolog A, Dual specicity protein phosphatase CDC 14A, Dual specicity protein phosphatase CDC14A, hCDC14, CC14A_HUMAN.

Background: In budding yeast, the Cdc14a phosphatase activates mitotic exit by dephosphorylation of specific cyclin-dependent kinase (Cdk) substrates and seems to be regulated by sequestration in the nucleolus until its release during mitosis. Human Cdc14a phosphatase is highly similar to Saccharomyces cerevisiae Cdc14 and is a member of the dual specificity protein Tyrosine phosphatase family. It interacts with and dephosphorylates tumor suppressor protein p53 and may regulate the function of p53. In addition, Cdc14a dephosphorylates hCdh1 and activates APCCdh1. Cdc14a phosphatase plays a role in the regulation of the centrosome cycle, mitosis and cytokinesis, thereby influencing chromosome partitioning and genomic stability in human cells. Deregulated human Cdc14a phosphatase disrupts centrosome separation and chromosome segregation.

ID gène: 8556

UniProt: Q9UNH5